Evaluation of atopic dermatitis severity using artificial intelligence.

Atopic dermatitis is a prevalent and persistent chronic inflammatory skin disorder that poses significant challenges when it comes to accurately assessing its severity. The aim of this study was to evaluate deep learning models for automated atopic dermatitis severity scoring using a dataset of Aceh ethnicity individuals in Indonesia. The dataset of clinical images was collected from 250 patients at Dr.

larvae: A novel source for combating broad-spectrum bacterial and fungal infections.

Antimicrobial resistance is a growing concern due to the growth of antibiotic-resistant microorganisms, which makes it difficult to treat infection. Due to its broad-spectrum antimicrobial properties against a diverse array of bacteria, both Gram-positive and Gram-negative bacteria, and fungi, larval antimicrobial peptides (AMPs) have demonstrated potential as antimicrobial agents for the treatment of microbial infections and prevention of antibiotic resistance. This study emphasizes the unexplored mechanisms of action of larvae against microorganisms.

Antimicrobial Potential of Beetle Larval Haemolymph Against Methicillin-Resistant and .

<b>Background and Objective:</b> The emergence of methicillin-resistant community-acquired <i>Staphylococcus aureus </i>and antibiotic-resistant <i>Neisseria gonorrhoeae</i> has raised significant concerns. Efforts to combat resistance involve the exploration of novel alternative therapies, particularly those derived from insect components. <i>Rhynchophorus</i> sp.

Therapeutic potential of propolis in alleviating inflammatory response and promoting wound healing in skin burn.

Burns can cause inflammation and delayed healing, necessitating alternative therapies due to the limitations of conventional treatments. Propolis, a natural bee-produced substance, has shown promise in facilitating burn healing. This literature review provides a comprehensive overview of propolis' mechanisms of action, wound-healing properties, and its application in treating skin burns.

A Review of the Antimicrobial Potential of as a Natural Approach with Promising Prospects to Countermeasure Antibiotic Resistance.

Drug-resistant pathogens have become a serious public health concern worldwide considering the rapid emergence and distribution of new strains, which outpace the development of antimicrobial drugs. It is a complex and serious clinical problem that can cause an epidemic of a disease; consequently, numerous research studies are conducted to determine the solution to these problems, including the development of new antibiotics derived from natural sources such as insects. The housefly (), an insect known as a cosmopolitan pest, possesses several qualities that can ameliorate diseases; consequently, they can be used as a bioactive component in the development of medicines.

Crusted Scabies, a Neglected Tropical Disease: Case Series and Literature Review.

Crusted scabies is a rare form of scabies that presents with more severe symptoms than those of classic scabies. It is characterized by large crusted lesions, extensive scales, thick hyperkeratosis, and contains a large number of highly contagious itch mites. Crusted scabies is more prevalent in immunocompromised, malnourished, and disabled individuals.

Fruit Bromelain-Derived Peptide Potentially Restrains the Attachment of SARS-CoV-2 Variants to hACE2: A Pharmacoinformatics Approach.

Before entering the cell, the SARS-CoV-2 spike glycoprotein receptor-binding domain (RBD) binds to the human angiotensin-converting enzyme 2 (hACE2) receptor. Hence, this RBD is a critical target for the development of antiviral agents. Recent studies have discovered that SARS-CoV-2 variants with mutations in the RBD have spread globally.

Mucocutaneous mycoses in people living with human immunodeficiency virus in Indonesia.

Background: To date, integrated care for people living with human immunodeficiency virus (PLHIV) has improved. However, although the management of mucocutaneous mycosis cases has improved, disease progression might be different in immunocompromised patients, which leads to variable clinical manifestations.

Objectives: To describe the characteristics of mucocutaneous mycosis cases in the PLHIV population and its associated factors in Indonesia.

A Comprehensive Review of the Potential Use of Green Tea Polyphenols in the Management of COVID-19.

Green tea is produced from (L.) buds and leaves that have not gone through the oxidation and withering processes used to produce black and oolong teas. It was originated in China, but its cultivation and production have expanded to other Eastern Asian countries.

In Silico and In Vitro Evaluation of the Antimicrobial Potential of Isolated from Gut against .

Antimicrobial resistance is a major public health and development concern on a global scale. The increasing resistance of the pathogenic bacteria to antibiotics necessitates efforts to identify potential alternative antibiotics from nature, including insects, which are already recognized as a source of natural antibiotics by the scientific community. This study aimed to determine the potential of components of gut-associated bacteria isolated from , an Asian giant honeybee, as an antibacterial against by in vitro and in silico methods as an initial process in the stage of new drug discovery.

Potential of Plant Bioactive Compounds as SARS-CoV-2 Main Protease (M) and Spike (S) Glycoprotein Inhibitors: A Molecular Docking Study.

Since the outbreak of the COVID-19 (coronavirus disease 19) pandemic, researchers have been trying to investigate several active compounds found in plants that have the potential to inhibit the proliferation of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). The present study aimed to evaluate bioactive compounds found in plants using a molecular docking approach to inhibit the main protease (M) and spike (S) glycoprotein of SARS-CoV-2. The evaluation was performed on the docking scores calculated using AutoDock Vina (AV) as a docking engine.