An In Vitro Study for the Role of Schizophrenia-Related Potential miRNAs in the Regulation of COMT Gene.

This study aimed to analyze the possible association of miR-30a-5p, miR-30e-5p, and miR-34a-5p identified as potential candidate miRNAs in schizophrenia, with the COMT gene. Candidate miRNAs were obtained from the TargetScan database. The SH-SY5Y human neuroblastoma cell line was used as a cellular model for schizophrenia.

Oral Rehabilitation with Implant-Retained Overdenture in a Patient with Down Syndrome.

Down syndrome, known as trisomy 21, is the most common chromosomal disorder. The disorder affects mental and systemic development as well as oral structure, including dental anomalies, high susceptibility of periodontal disease, and poor quality of alveolar bone. This report presents a case of dental rehabilitation by means of dental implants of a patient with Down syndrome.

Is Hyaluronic Acid Injection Effective for the Treatment of Temporomandibular Joint Disc Displacement With Reduction?

Purpose: Hyaluronic acid (HA) injections and occlusal splints have been suggested in the treatment of temporomandibular joint (TMJ) derangements, but no sufficient data are available from controlled clinical trials comparing HA injection with another treatment modality. This study compared the effectiveness of a single HA injection, a double HA injection, and splint therapy for the treatment of TMJ disc displacement with reduction (DDR).

Materials And Methods: A prospective clinical trial was designed.

Reduction of isolated zygomatic arch fractures using dental instrument: Report of 2 cases and review of the literature.

To assess the effectiveness of a dental instrument for reduction of isolated zygomatic arch fractures. Two patients were admitted to our clinic representing isolated unilateral zygomatic arch fracture. The common presenting complaints were pain, swelling and difficulty in mouth opening.

Effects of osteoformin in the rapid distraction osteogenesis of rabbit mandibles.

Objective: To evaluate the effects of osteoformin on mineralisation and quality of the new bone formation during rapid distraction osteogenesis.

Methods: This multi-centre study was conducted at the Karadeniz Technical University, Middle East Technical University and Selcuk University. The experimental study was conducted from January 2010 to September 2012 and comprised New-Zealand rabbits that were randomly divided into three groups.

Novel retromandibular subparotideomasseteric fascial approach for placement of a temporomandibular joint prosthesis.

For placement of a temporomandibular joint prosthesis, preauricular and retromandibular approaches are used. The main complication of the retromandibular approach is marginal mandibular nerve damage. In this technical study, the retromandibular subparotideomasseteric fascial approach is introduced as an alternative to avoid the complications of the conventional retromandibular approach.

Comparative radiologic analyses of newly formed bone after maxillary sinus augmentation with and without bone grafting.

Purpose: The present study examined the formation and density of new bone after sinus membrane elevation, with and without bone grafting, and evaluated the bone formation at the apices of the implants with these 2 different maxillary sinus floor elevation techniques.

Materials And Methods: In a prospective randomized controlled study design, patients requiring reconstruction of their atrophic maxilla were included and divided randomly into grafted and nongrafted groups. Implants were inserted in each group by way of sinus membrane elevation.

Evaluation of sedation in oral and maxillofacial surgery in ambulatory patients: failure and complications.

Objectives: This study evaluated the failure and complication rates of sedation in ambulatory patients undergoing oral and maxillofacial surgery.

Materials And Methods: This retrospective cohort study was carried out among 619 patients who had undergone maxillofacial surgical procedures under intravenous sedation with midazolam and fentanyl. Each patient's age, American Society of Anesthesiologists (ASA) classification, systemic condition, surgical procedure, complications, and failures were recorded for evaluation.

A 3-year follow-up of the rehabilitation of Papillon-Lefèvre syndrome by dental implants.

Purpose: Papillon-Lefèvre syndrome is a rare autosomal recessive genetic disorder characterized by palmar-plantar hyperkeratosis, with rapidly progressive periodontitis and premature loss of both deciduous and permanent teeth. This article presents the prosthetic rehabilitation of a patient with Papillon-Lefèvre syndrome with dental implants.

Materials And Methods: Twelve titanium implants were installed in the mandible and maxilla in an 18-year-old male patient with Papillon-Lefèvre syndrome.

[The relationship between paraoxanase gene Leu-Met (55) and Gln-Arg (192) polymorphisms and coronary artery disease].

Objectives: Paraoxonase (PON1) is a high-density lipoprotein (HDL)-associated esterase that hydrolyses lipoperoxides. PON1 serves as a protective factor against oxidative modification of LDL, suggesting that it may play an important role in the prevention of atherosclerotic process. Research has focused on two polymorphisms: leucine (L allele) to methionine (M allele) substitution at codon 55, and glutamine (A allele) to arginine (B allele) substitution at codon 192.

[A study of sister chromatid exchange (SCE) in patients with liver cystic hydatid disease who have been treated with albendazole.].

A total of 21 patients including 13 females and 8 males who presented at the Microbiology and General Surgery Departments of the Atatürk Research and Training Hospital with complaints of liver cystic hydatid disease have been included in this study. Albendazole was administered to these cystic hydatid patients before and after surgery. The aim of this study was to investigate the probable genotoxic effects of albendazole.