Introduction of mosquitoes carrying AlbB sharply decreases dengue incidence in disease hotspots.

Partial replacement of resident mosquitoes with introduced mosquitoes carrying certain strains of inherited symbionts can result in transmission blocking of dengue and other viruses of public health importance. strain AlbB is an effective transmission blocker and stable at high temperatures, making it particularly suitable for hot tropical climates. Following trial field releases in Malaysia, releases using AlbB have become operationalized by the Malaysian health authorities.

Characterization of Sodium Channel Mutations in the Dengue Vector Mosquitoes and within the Context of Ongoing Releases in Kuala Lumpur, Malaysia.

Specific sodium channel gene mutations confer target site resistance to pyrethroid insecticides in mosquitoes and other insects. In mosquito species, multiple mutations that contribute to resistance vary in their importance around the world. Here, we characterize voltage sensitive sodium channel () mutations in populations of from Kuala Lumpur, Malaysia, and look at their persistence in populations affected by ongoing releases (a dengue control measure).