Publications by authors named "Nur Syazana Roslan"
Genes (Basel)
November 2022
Article Synopsis
- The study explores a non-invasive method for diagnosing fetal aneuploidy by isolating fetal nucleated red blood cells (FNRBCs) from maternal blood, eliminating the miscarriage risks associated with invasive procedures like CVS and amniocentesis.!*
-
- Researchers successfully used whole-genome amplification and semiconductor sequencing on single FNRBCs to classify fetal genotypes, achieving accurate results for normal and aneuploidy cases, including trisomies for chromosomes 15, 21, and 18.!*
-
- The approach not only provided 100% accuracy in determining fetal genetic status but also correctly identified fetal sex in all tested cases, highlighting the potential for reliable non-invasive prenatal diagnostics.!
