Publications by authors named "Nur Izzati Huda Zulkarnain"

Introduction: Magnetic resonance imaging (MRI) provides excellent soft tissue contrast for visualizing of deep brain stimulation (DBS) targets, allowing validation of the electrode placement, and assessing complications such as microhemorrhage and edema. However, the presence of the electrodes can introduce challenges such as radiofrequency (RF) induced current artifacts and excessive heating of the electrode contacts. Additionally, extended procedure times are also considered a disadvantage when using MRI as an intraoperative imaging modality following DBS electrode placement.

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Background: Heating around deep brain stimulation (DBS) in magnetic resonance imaging (MRI) occurs when the time-varying electromagnetic (EM) fields induce currents in the electrodes which can generate heat and potentially cause tissue damage. Predicting the heating around the electrode contacts is important to ensure the safety of patients with DBS implants undergoing an MRI scan. We previously proposed a workflow to predict heating around DBS contacts and introduced a parameter, equivalent transimpedance, that is independent of electrode trajectories, termination, and radiofrequency (RF) excitations.

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Article Synopsis
  • The study aims to develop a method for identifying implant-friendly (IF) excitation modes in multichannel RF coils used during deep brain stimulation (DBS) to reduce RF heating at electrode contacts in a 7T MRI environment.
  • Researchers utilized a technique to calculate the induced RF currents on DBS electrodes and determine the IF modes by analyzing the magnetic fields produced by a multichannel RF coil.
  • Testing showed that the new IF modes did not significantly raise temperatures in the electrodes, while the conventional methods led to over 2°C increases, demonstrating the effectiveness of the proposed strategy.
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Purpose: The purpose of this study is to present a workflow for predicting the radiofrequency (RF) heating around the contacts of a deep brain stimulation (DBS) lead during an MRI scan.

Methods: The induced RF current on the DBS lead accumulates electric charge on the metallic contacts, which may cause a high local specific absorption rate (SAR), and therefore, heating. The accumulated charge was modeled by imposing a voltage boundary condition on the contacts in a quasi-static electromagnetic (EM) simulation allowing thermal simulations to be performed with the resulting SAR distributions.

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