Uncovering anti-inflammatory potential of Linn: Network pharmacology and in vitro studies.

Linn contains a diverse array of metabolites that exhibit therapeutic potential. The aim of this study was to evaluate the potential of leaves, which were collected at the Ie-Seu'um geothermal area in Aceh, Indonesia, as an anti-inflammatory through network pharmacology and in vitro analysis. The ethanolic extract derived from underwent identification utilizing gas chromatography-mass spectrometry (GC-MS) to verify chemical constituents for drug-likeness properties.

Clinical and oral microbiome pattern of halitosis patients with periodontitis and gingivitis.

Halitosis is caused by a bacterial proteolytic process that induces the production of volatile sulfur compounds, odor-causing gases. The aim of this study was to determine the clinical oral hygiene state and oral microbiome pattern of halitosis patients with periodontitis and gingivitis. The oral hygiene state of halitosis patients with periodontitis and gingivitis was assessed using the oral hygiene index simplified (OHI-S), decay missing filled teeth (DMFT), and tongue biofilm.

In Silico and In Vitro Analysis of Tacca Tubers () from Banyak Island, Aceh Singkil Regency, Indonesia, as Antihypercholesterolemia Agents.

() contain a number of active compounds such as flavonoids, tannins, phenolics, steroids, and alkaloids. The active compounds from plants have been shown to reduce the risk of cardiovascular disease by lowering cholesterol levels by inhibiting the enzyme 3-hydroxy-3-methylglutaryl-coenzym A (HMG-CoA) reductase activity. This study aims to investigate the potential active compounds in the ethanolic extract of Tacca tubers () from the Banyak Islands, Aceh Singkil Regency, Aceh Province both in vitro and in silico.