Publications by authors named "Nur Astiana Mawan"
Article Synopsis
- * The upregulation of IQGAP3 in cancer is linked to the re-expression of IGF2BP1, which stabilizes its transcripts and promotes its growth-stimulating effects.
- * Understanding how IQGAP3 expression is regulated could lead to new drug targets to prevent cancer growth driven by aberrant stem cell proliferation.
Objective: Tissue stem cells are central regulators of organ homoeostasis. We looked for a protein that is exclusively expressed and functionally involved in stem cell activity in rapidly proliferating isthmus stem cells in the stomach corpus.
Design: We uncovered the specific expression of Iqgap3 in proliferating isthmus stem cells through immunofluorescence and in situ hybridisation.