Regulatory Mechanism on Anti-Glycolytic and Anti-Metastatic Activities Induced by in Breast Cancer, In Vitro.

An active fraction of , F3, and its bioactive compounds (lutein, β-sitosterol, and stigmasterol) were reported to have anti-glycolytic activities in MDA-MB-231 cells. Since glycolysis can also regulate metastatic activities in cancer cells, this study investigated the mechanism underlying the anti-glycolytic and anti-metastatic activities induced by F3 and its bioactive compounds on MDA-MB-231 cells. The cells were treated with IC concentrations of F3, lutein, β-sitosterol, and stigmasterol.