Objective: To observe the effect of moxibustion on the learning ability and expression of neurotrophic factors and Notch signaling in vascular dementia (VD) rats, so as to explore its neurogenesis mechanism underlying improvement of VD.
Methods: Sixty SD rats were equally and randomly divided into sham operation (sham), model, medication and moxibustion groups (=15 rats/group). The VD model was established by occlusion of the bilateral cervical common arteries and reperfusion.