Metastatic cancer and endentulism: Exploring comorbidity to assist with differential diagnosis in a case from Vico nel Lazio (Fr, Italy), 13th-15th century CE.

Objective: To differentially diagnose cranial lesions noted on a medieval skeleton and explore the importance of comorbidity.

Materials: A skull of an adult female with osteolytic and osteoblastic lesions, edentulism, and an ectopic tooth from an ossuary of the Church of Santa Maria in Vico del Lazio, Frosinone Italy, dating to the Middle Ages.

Methods: Macroscopic observations of the remains, CT scan, and differential diagnosis was undertaken.

Biological history of an Italian prehistoric community and the population of the central Italy during the 1 millennium BCE.

Understanding the population of Central Italy during the 1 millennium BCE is a crucial topic in the biological history of the Mediterranean basin. This period saw the emergence of the Etruscan and Roman cultures which had a significant impact on the bio-cultural history of the region. In this study, we analyse a prehistoric population from Caracupa (Iron Age, Latium, Central Italy).