Publications by authors named "Nuno Pereira da Silva"

This article discusses the application of three-dimensional (3D) printing in reconstructing the orbital floor of a middle-aged male patient who suffered an orbital fracture due to a fall. A virtual 3D model of the fractured orbit was created using open-source software, allowing for the planning of the defect reconstruction by mirroring the contralateral orbit. A metal reconstruction plate was then molded based on the 3D printed model, sterilized, and utilized during surgery, which resulted in reduced surgical time and improved adaptation.

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Article Synopsis
  • The study looked at how inflammation affects bone density in people's spines who have a condition called radiographic axial spondyloarthritis (r-axSpA).
  • Researchers found that inflammation was linked to lower bone density, but lower bone density didn't actually lead to new bone growth over 2 years.
  • The conclusion is that it’s more important to focus on reducing inflammation to prevent bone issues than just trying to fix the bone density itself.
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Objectives: To describe low dose Computed Tomography (ldCT) Hounsfield Units (HU) two-year change-from-baseline values (expressing trabecular bone density changes) and analyse their inter-reader reliability per vertebra in radiographic axial spondyloarthritis (r-axSpA).

Methods: We used 49 patients with r-axSpA from the multicentre two-year Sensitive Imaging in Ankylosing Spondylitis (SIAS) study. LdCT HU were independently measured by two trained readers at baseline and two years.

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Advances in robotic construction are evident and increasing every year, bringing present and potential improvements. However, the economic and social impacts are hard to assess and quantify without physical in situ testing, which is expensive and time-consuming. This paper presents a methodology for the simulation of robotic construction technologies, namely drones, using a virtual reality environment.

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Negative pressure pulmonary edema (NPPE) in the context of anesthesia is a rare condition, although pediatric patients are at higher risk. This case stands out for the severe respiratory clinic that quickly developed in a child with a cancer history whose radiological and clinical presentation suggested multiple differential diagnoses, including tumor recurrence with metastasis or pulmonary tuberculosis. NPPE is a well-described, but a probably underrecognized clinical syndrome, that occurs after intense inspiratory effort against an obstructed airway.

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Objective: Studying vertebral bone loss in radiographic axial spondyloarthritis (r-axSpA) has been challenging due to ectopic bone formation. We cross-sectionally analysed low-dose CT (ldCT) trabecular bone density Hounsfield units (HU) measurements and calculated inter-reader reliability at the vertebral level in patients with r-axSpA.

Methods: LdCT scans of 50 patients with r-axSpA from the sensitive imaging in ankylosing spondylitis study, a multicentre 2-year prospective cohort were included.

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Perioperative management of patients with mediastinal masses still poses a challenge for the anesthesiologist, as the use of general anesthesia can be associated with acute perioperative cardiorespiratory impairment resulting from the mass collapsing on the airway or vascular structures. Dexmedetomidine can be used for procedural sedation due to its reversible sedative and anxiolytic properties with dose-dependent effects, while not interfering with ventilatory drive. These features are of particular interest for the perioperative management of patients with large anterior mediastinal masses.

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Background: Fluorine-18 sodium fluoride (Na[F]F) atherosclerotic plaque uptake in positron emission tomography with computed tomography (PET-CT) identifies active microcalcification. We aim to evaluate global cardiac microcalcification activity with Na[F]F, as a measure of unstable microcalcification burden, in high cardiovascular (CV) risk patients.

Methods And Results: Thirty-four high CV risk individuals without previous CV events were scanned with Na[F]F PET-CT.

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Background: Three-dimensional (3D) models are increasingly used to help surgeons, guiding them through the complex hepatic vasculobiliary anatomy. The biliary tract is a relatively untapped territory with only a few case reports described in medical literature. Our aim is to present an innovative 3D reconstruction methodology for biliary imaging and surgical planning, applied to a case of iatrogenic biliary stricture, with fusion of segmented CT and MRI images.

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