Neuroimaging characterization of multiple sclerosis lesions in pediatric patients: an exploratory radiomics approach.

Introduction: Multiple sclerosis (MS), a chronic inflammatory immune-mediated disease of the central nervous system (CNS), is a common condition in young adults, but it can also affect children. The aim of this study was to construct radiomic models of lesions based on magnetic resonance imaging (MRI, T2-weighted-Fluid-Attenuated Inversion Recovery), to understand the correlation between extracted radiomic features, brain and lesion volumetry, demographic, clinical and laboratorial data.

Methods: The neuroimaging data extracted from eleven scans of pediatric MS patients were analyzed.

Investigating Inattentional Blindness Through the Lens of Fear Chemosignals.

is a phenomenon wherein people fail to perceive obvious stimuli within their vision, sometimes leading to dramatic consequences. Research on the effects of fear chemosignals suggests that they facilitate receivers' sensory acquisition. We aimed to examine the interplay between these phenomena, investigating whether exposure to fear chemosignals (vs.

Comparing fear and anxiety chemosignals: Do they modulate facial muscle activity and facilitate identifying facial expressions?

Fear and anxiety are the most frequently studied emotional states in chemosignal research. Despite differences between these two emotional states, findings from research using fear and anxiety body odors (BOs) are often treated as part of a similar phenomenon. In this article, we examine possible similarities and differences between participants exposed to fear and anxiety BOs on 2 dependent variables commonly used in chemosignals' research: (1) the activation of facial muscles in displays of fear expressions (i.

Disentangling the Role of the SnO Layer on the Pyro-Phototronic Effect in ZnO-Based Self-Powered Photodetectors.

Self-powered photodetectors (PDs) have been recognized as one of the developing trends of next-generation optoelectronic devices. Herein, it is shown that by introducing a thin layer of SnO film between the Si substrate and the ZnO film, the self-powered photodetector Al/Si/SnO/ZnO/ITO exhibits a stable and uniform violet sensing ability with high photoresponsivity and fast response. The SnO layer introduces a built-in electrostatic field to highly enhance the photocurrent by over 1000%.

Checklist of water mites from mainland Portugal and its archipelagos.

This study focuses on aquatic mites from the Portuguese Exclusive Economic Zone, including the mainland area, and Madeira and Azores archipelagos, aiming at compiling all existing information and generating a list of species and all their data on collecting sites. For the present work, we consider aquatic species, those that inhabit the marine, deep sea, intertidal, freshwater, transition water or brackish environments, with life-cycle occurring entirely at water habitats or their vicinity. Furthermore, breeding should take place in water aquatic lifestyles.

Validation of the open biological negative image set for a Portuguese population: Comparing Japanese and Portuguese samples and an exploration of low-order visual properties of the stimuli.

Recently, Shirai and Watanabe Royal Society Open Science, 9(1), 211128 (2022) developed OBNIS (Open Biological Negative Image Set), a comprehensive database containing images (primarily animals but also fruits, mushrooms, and vegetables) that visually elicit disgust, fear, or neither. OBNIS was initially validated for a Japanese population. In this article, we validated the color version of OBNIS for a Portuguese population.

A Survey on Wearable Sensors for Mental Health Monitoring.

Mental illness, whether it is medically diagnosed or undiagnosed, affects a large proportion of the population. It is one of the causes of extensive disability, and f not properly treated, it can lead to severe emotional, behavioral, and physical health problems. In most mental health research studies, the focus is on treatment, but fewer resources are focused on technical solutions to mental health issues.

Discrepancy in Reporting of Perioperative Complications: A Retrospective Observational Study.

Objective: To assess the discrepancy between perioperative complications, prospectively recorded during a cohort study versus retrospectively from health records.

Background: Perioperative adverse events are relevant for patient outcome, but incomplete reporting is common.

Methods: Two physicians independently recorded all intraoperative adverse events according to ClassIntra and all postoperative complications according to the Clavien-Dindo classification based on all available health records.

Flexible Neural Probe Fabrication Enhanced with a Low-Temperature Cured Polyimide and Platinum Electrodeposition.

Polyimide is an emerging and very interesting material for substrate and passivation of neural probes. However, the standard curing temperature of polyimide (350 °C) is critical for the microelectrodes and contact pads of the neural probe, due to the thermal oxidation of the metals during the passivation process of the neural probe. Here, the fabrication process of a flexible neural probe, enhanced with a photosensitive and low-temperature cured polyimide, is presented.

Aseptic Pustulosis of the Folds Successfully Treated with Methotrexate.

An otherwise healthy 47-year-old woman presented with confluent pustular lesions on the scalp for 5 months and asymptomatic pustular lesions on the trunk and extremities for 2 weeks. She did not have systemic clinical manifestations and was treated with oral antifungals and antibiotics (amoxicillin, and clavulanic acid and flucloxacillin), with no effect. The lesions were unrelated to her menstrual cycle, and she had no history of dermatosis, including acne, psoriasis, or folliculitis.

Normolipemic Plane Xanthoma.

A 77-year-old man, otherwise healthy, presented with multiple symmetric yellowish patches in his axillary folds and abdomen that had evolved for 6 months (Figures 1 and 2). The lesions were initially confined to the axillary folds but have since disseminated during last 3 months. The patient was asymptomatic, and the physical examination was normal.

Can Humans Discriminate Horse 'Fear' Chemosignals from Control Chemosignals? Comment on Sabiniewicz et al. A Preliminary Investigation of Interspecific Chemosensory Communication of Emotions: Can Humans () Recognise Fear- and Non-Fear Body Odour from Horses (). 2021, , 3499.

We illustrate the problematic nature of different assumptions guiding the examination of whether humans can detect the source of fear chemosignals (i.e., body odors) emitted by horses-a research question examined in an article recently published in .

A Delphi study on the clinical management of age-related macular degeneration.

Purpose: Age-related macular degeneration (AMD) is one of the main causes of blindness and visual impairment worldwide. As achieving a dry macula is one of the main objectives in AMD management, the purpose of this work was to reach a consensus on the relevance of retinal fluid in function, disease activity control and treatment patterns.

Methods: Forty-seven Portuguese ophthalmologists specialized in AMD participated in a DELPHI panel.

Subacromial resurfacing with fascia lata autograft for irreparable cuff tears : JEO 2021 expert opinion short report & surgical technique with video.

Massive and irreparable rotator cuff tears remain a major challenge for orthopaedic surgeons and several surgical options have been accepted for different patterns of irreparable cuff tears. However, the high-cost and technical complexity of some surgeries and the inconsistent clinical results of others, leave room for the search for surgical options that can offer a good balance between technical simplicity, a lower cost and an acceptable clinical result.The rationale behind some available techniques includes lowering the humeral head, which enables a more efficient balance of the force couples around the shoulder during rehabilitation.

Guidelines for the Management of Center-Involving Diabetic Macular Edema: Treatment Options and Patient Monitorization.

Diabetic macular edema (DME) is the main cause of visual impairment associated with diabetic retinopathy (DR) and macular laser, during approximately three decades, and was the single treatment option. More recently, intravitreous injections of anti-angiogenics and corticosteroids modified the treatment paradigm associated with significant vision improvements. Nevertheless, not all patients respond satisfactorily to anti-VEGF or corticosteroid injections, so an adequate treatment choice and a prompt switch in therapeutic class is recommended.

Langerhans Cell Histiocytosis-A Benign Presentation Heralding a Serious Disease.

A 3-year old White boy was referred to our dermatology department with a papular disseminated eruption, evolving for 7 months. Several topical antibiotics and corticosteroids were used without improvement. The dermatosis was locally asymptomatic, and systemic symptoms were absent.

Cutaneous metastasis of a hypopharyngeal squamous cell carcinoma-unusual presentation.

Cutaneous metastasis are uncommon and account for only 2% of all skin cancers, but are extremely rare in hypopharyngeal carcinomas. Although often associated with advanced cancer, cutaneous metastasis can be the first indication of relapse or treatment failure. Additionally, the clinical presentation is widely variable, which can make an early diagnosis difficult.