Publications by authors named "Nungshioba Jamir"
Article Synopsis
- A protein-drug binding study investigates how drugs like sulfamethazine (SMZ) and sulfadiazine (SDZ) interact with the protein lysozyme (Lyz), using techniques like spectroscopy and molecular simulations.
- The study finds that SMZ has a slightly higher binding affinity than SDZ, with a 1:1 binding ratio and a spontaneous, exothermic reaction driven by enthalpy and entropy changes.
- Results also reveal a static quenching mechanism affecting the protein's tryptophan structure, and molecular docking shows that SMZ occupies the drug binding pocket of Lyz more effectively than SDZ.
