Publications by authors named "Nugraha Utama Pelupessy"
Objective: This study aimed to evaluate the relationship between mannose-binding lectin-associated serine protease-2 as an immune system parameter and neutrophil lymphocyte ratio (NLR) as an inflammatory parameter to predict cervical cancer metastasis.
Materials And Methods: This cross-sectional study included 70 patients diagnosed with cervical cancer between January 2022 and February 2023 at Dr. Wahidin Sudirohusodo Hospital, Hasanuddin University Hospital, and Ibnu Sina Hospital, Makassar, Indonesia.
Cervical cancer mostly caused by Human Papilloma Virus. Staging and therapy have been extensively studied, and highly correlated with the cellular development of oncogenesis. Mutation was caused by E6 and E7 oncoprotein, also inactivation of 2 tumor suppressor factors (pRB and p53).
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- * A total of 57 women with preeclamptic pregnancies and 30 women with normal pregnancies were included, with ADMA measured using the ELISA method during the third trimester.
- * Results showed that ADMA levels were significantly higher in women with preeclampsia and correlated positively with blood pressure and certain kidney markers, indicating a strong relationship between ADMA levels and preeclampsia.