Cognitive enhancement and neuroprotective effects of a traditional Chinese herbal compound medicine on Aβ1-42 induced Alzheimer's disease in rats.

Introduction: We aimed to explore the role of a novel traditional herbal compound medicine (HCM) in Alzheimer's disease (AD).

Material And Methods: 72 rats were randomized into control, AD, Donepezil and HCM groups. Injection of -amyloid peptide (A1-42) into the lateral ventricle was used to induce AD in rats.