Publications by authors named "Nuerailijiang Maimaitiaili"
Dural injuries often result in severe complications such as cerebrospinal fluid (CSF) leakage, intracranial infections, and brain herniation, which significantly impact patient recovery and quality of life. Conventional dural repair materials, which rely on suturing to peripheral tissues, fail to promote tissue regeneration and provide sufficient CSF leakage prevention, leading to suboptimal outcomes. To address these limitations, we developed a Janus adhesive bio-patch with both antibacterial and pro-angiogenic properties to enhance dura mater repair.
View Article and Find Full Text PDFSpinal cord injury (SCI) is a severe condition that often leads to permanent functional impairments. The current treatment options are limited and there is a need for more effective treatments. Human umbilical cord mesenchymal stem cells (hUCMSCs) have shown promise in promoting neuroregeneration and modulating immune response.
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- Low-grade gliomas (LGG) are serious brain tumors, and this study aims to identify genes linked to patient survival using CRISPR-cas9 data and RNA sequencing.
- Researchers found 145 oncogenes in LGG and used these to create a genetic signature of 19 genes, which was effective in distinguishing between low-risk and high-risk patients, revealing that high-risk patients have shorter survival rates.
- The study highlighted the Hippo signaling pathway as a key regulator of tumor growth, suggesting it could be a new target for treatment in patients with low-grade gliomas.