Publications by authors named "Nuanjan Wichukchinda"
Cell Host Microbe
November 2024
Article Synopsis
- Tuberculosis caused by Mycobacterium tuberculosis (Mtb) remains a major global health concern, and this study introduces a new method to identify large genetic insertions and deletions (indels) that have been overlooked.
- The analysis of 1,960 Mtb clinical isolates shows that harmful genetic variants are rarely found in essential survival genes, while Mtb genomes contain many partially harmful mutations.
- The research also links specific genetic variations, including indels in various genes, to patient outcomes and antibiotic resistance, offering insights that could improve tuberculosis treatment and prediction of risks.
