Synthesis, Characterization and In Vitro Antibacterial Evaluation of Conjugated Silver Nanoparticles.

In the present study, silver nanoparticles (AgNPs) were synthesized using both the chemical and biological methods and conjugated with extracts. These were then characterized and evaluated for antimicrobial activities against multi-drug resistant pathogens, such as methicillin-resistant (MRSA), and . Nanoparticles were analyzed with UV-visible spectrophotometer, transmission electron microscopy (TEM), and energy dispersive X-ray analysis (EDX).

Peptide-functionalized quantum dots for potential applications in the imaging and treatment of obesity.

Background: Obesity is a worldwide epidemic affecting millions of people. The current pharmacological treatment of obesity remains limited and ineffective due to drugs' undesirable side effects. Hence, there is a need for novel or improved strategies for long-term therapies that will help prevent the disease progression into other chronic diseases.

Peptide-functionalized nanoparticles for the selective induction of apoptosis in target cells.

Aim: The study developed a prohibitin (PHB) targeted nanotherapy for selective induction of apoptosis in target cells.

Methods: Gold nanoparticles (AuNPs) were bifunctionalized with adipose homing and proapoptotic peptides. The efficacy and mode of cell death induced by the AuNPs were investigated in vitro on three cancer cell lines.

Imino-phosphine palladium(II) and platinum(II) complexes: synthesis, molecular structures and evaluation as antitumor agents.

The imino-phosphine ligands L1 and L2 were prepared via condensation reaction of 2-(diphenylphosphino)benzaldehyde with substituted anilines and obtained in very good yields. An equimolar reaction of L1 and L2 with either PdCl2(cod) or PtCl2(cod) gave new palladium(II) and platinum(II) complexes 1-4. The compounds were characterized by elemental analysis, IR, (1)H and (31)P NMR spectroscopy.