Publications by authors named "Nsabimana Eliphaz"
Article Synopsis
- Staphylococcus xylosus, a gram-positive bacterium, is increasingly linked to serious drug resistance issues, making its study significant.
- The research investigates the role of L-lactate dehydrogenase (LDH) in multidrug resistance using genetically modified S. xylosus strains, where LDH was knocked out and complemented.
- Findings reveal that knocking out LDH increases antibiotic resistance, particularly to lincomycin, and alters key metabolic pathways, indicating that LDH deficiency enhances drug resistance by disrupting the TCA cycle and thioredoxin system.
Stress diarrhea is a major challenge for weaned piglets and restricts pig production efficiency and incurs massive economic losses. A traditional Chinese medicine prescription (QJC) composed of Schischkin (HQ), Roscoe (SJ), and L. (CQC) has been developed by our laboratory and shows marked anti-stress diarrhea effect.
View Article and Find Full Text PDFL. is a natural medicinal plant that has been widely used for its various pharmacological effects such as antidiarrheal, anti-inflammatory, and wound healing. This study aims to explore the antidiarrheal active ingredients of L.
View Article and Find Full Text PDFBioactive compounds from Traditional Chinese Medicines (TCMs) are gradually becoming an effective alternative in the control of porcine reproductive and respiratory syndrome virus (PRRSV) because most of the commercially available PRRSV vaccines cannot provide full protection against the genetically diverse strains isolated from farms. Besides, the incomplete attenuation procedure involved in the production of modified live vaccines (MLV) may cause them to revert to the more virulence forms. TCMs have shown some promising potentials in bridging this gap.
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- * Results showed that higher light intensity (50-60%) significantly increased the rutin levels compared to lower intensities, linking light conditions to enhanced flavonoid production.
- * The research identified key genes involved in the flavonoid biosynthetic pathway, suggesting that they could be potential targets for further studies to optimize the medicinal qualities of S. oblata.
Article Synopsis
- Lindl. is a plant that can fight bacteria and stop them from forming protective layers called biofilms.
- The study tested different ways to prepare the plant to make it work better against these biofilms.
- The best method was stir-frying the plant with vinegar, which helped reduce certain harmful substances and showed that it could effectively treat infections.
Glutamine synthetase (GS), which catalyzes the production of glutamine, plays essential roles in most biological growth and biofilm formation, suggesting that GS may be used as a promising target for antibacterial therapy. We asked whether a GS inhibitor could be found as an anti-infective agent of (). Here, computational prediction followed by experimental testing was used to characterize GS.
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