Publications by authors named "Nrateng Tsotetsi"
Cervical cancer is ranked the fourth most common cause of cancer related deaths amongst women. The situation is particularly dire in low to lower middle-income countries. It continues to affect these countries due to poor vaccine coverage and screening.
View Article and Find Full Text PDFArticle Synopsis
- Broad-spectrum β-lactam antibiotics like penicillin are commonly used against various bacteria, but resistance has developed due to β-lactamase enzymes which deactivate these antibiotics.
- 1,4,7-Triazacyclononane (TACN), a compound that inhibits β-lactamase, was tested for cytotoxicity on human embryonic kidney cells (Hek293) through various assays, showing it does not induce necrosis or significant apoptosis.
- The study concluded that TACN does not harm Hek293 cells, suggesting its potential to restore the effectiveness of β-lactam antibiotics against resistant bacteria without causing cell death.