Publications by authors named "Nozomi Daimaruya"

Article Synopsis
  • This study explored how effectively sugammadex reverses the paralysis caused by rocuronium in dogs under anesthesia compared to a saline control.
  • Six adult Beagle dogs were used in a crossover study design, with each dog receiving alfaxalone anesthesia, rocuronium, and either sugammadex or saline.
  • Results showed that while the onset and maximum duration of neuromuscular blockade were similar between treatments, sugammadex significantly reduced recovery time and index compared to saline, suggesting it is a more effective reversal agent.
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Article Synopsis
  • The study aimed to find the effective doses of rocuronium that would depress muscle twitch response in dogs under alfaxalone anesthesia.
  • It included eight Beagle dogs, monitored through neuromuscular function to measure the effect of different doses of rocuronium (100, 175, and 250 μg/kg).
  • Results showed that the effective doses were 175 μg/kg for ED and 232 μg/kg for ED, with longer recovery times corresponding to higher doses of rocuronium.
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Article Synopsis
  • The study assessed the sedative effects of intranasal medetomidine in eight healthy Japanese White rabbits using a mucosal atomization device (MAD), with varying doses administered and a control saline treatment.
  • Doses of medetomidine were administered at three levels (0.3 mL to one nostril, 0.3 mL to both nostrils, and 0.3 mL twice to both nostrils), showing a clear, dose-dependent sedative effect as measured by loss of righting reflex (LRR) times.
  • Intranasal administration of medetomidine also resulted in significant cardiorespiratory depression, indicated by decreases in pulse
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