Publications by authors named "Nozomi Daimaruya"
Vet Anaesth Analg
November 2023
Article Synopsis
- This study explored how effectively sugammadex reverses the paralysis caused by rocuronium in dogs under anesthesia compared to a saline control.
- Six adult Beagle dogs were used in a crossover study design, with each dog receiving alfaxalone anesthesia, rocuronium, and either sugammadex or saline.
- Results showed that while the onset and maximum duration of neuromuscular blockade were similar between treatments, sugammadex significantly reduced recovery time and index compared to saline, suggesting it is a more effective reversal agent.
Vet Anaesth Analg
May 2023
Article Synopsis
- The study aimed to find the effective doses of rocuronium that would depress muscle twitch response in dogs under alfaxalone anesthesia.
- It included eight Beagle dogs, monitored through neuromuscular function to measure the effect of different doses of rocuronium (100, 175, and 250 μg/kg).
- Results showed that the effective doses were 175 μg/kg for ED and 232 μg/kg for ED, with longer recovery times corresponding to higher doses of rocuronium.
Article Synopsis
- The study assessed the sedative effects of intranasal medetomidine in eight healthy Japanese White rabbits using a mucosal atomization device (MAD), with varying doses administered and a control saline treatment.
- Doses of medetomidine were administered at three levels (0.3 mL to one nostril, 0.3 mL to both nostrils, and 0.3 mL twice to both nostrils), showing a clear, dose-dependent sedative effect as measured by loss of righting reflex (LRR) times.
- Intranasal administration of medetomidine also resulted in significant cardiorespiratory depression, indicated by decreases in pulse
