Publications by authors named "Noy Danino"
Purpose: Bronchial hyperresponsiveness (BHR), a hallmark of bronchial asthma, is typically diagnosed through a methacholine inhalation test followed by spirometry, known as the methacholine challenge test (MCT). While spirometry relies on proper patients' cooperation and precise execution of forced breathing maneuvers, we conducted a comparative analysis with the portable nanomaterial-based sensing device, SenseGuard™, to non-intrusively assess tidal breathing parameters.
Materials And Methods: In this prospective study, 37 adult participants with suspected asthma underwent sequential spirometry and SenseGuard™ measurements after inhaling increasing methacholine doses.
Purpose: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a complication of COPD that typically necessitates intensified treatment and hospitalization. It is linked to higher morbidity, mortality and healthcare spending. Assessment of therapy response for AECOPD is difficult due to the variability of symptoms and limitations in current measures.
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- Researchers studied how electrical activity affects the structure of neurons, specifically looking at the cytoskeleton, which gives neurons their shape.
- They used high-resolution electron microscopy to observe changes in the sciatic nerve of mice after applying different frequencies of electric pulses.
- The results showed that neuronal stimulation significantly reduced the density of key cytoskeletal proteins, suggesting that this chemical change may help facilitate neuronal function and shape in response to electrical signals.