[Specificity of visual event-related potentials to subthreshold presentation of erotic pictures in pedophilia].

Objective: To study visual event-related potentials (ERPs) associated with presentation of erotic pictures in backward masking condition in order to investigate perception, attention and information processing underlying the initiation and maintenance of abnormal sexual behavior in pedophilia.

Material And Methods: Participants (58 males committed sexual offenses against children) were divided into the pedophilia group (=38) and the control group without disorders of sexual preference (=20). Three types of stimuli were used: neutral pictures of nature (S1), adult heterosexual erotic pictures (S2) and erotic pictures with children (S3).

Mu rhythm separation from the mix with alpha rhythm: Principal component analyses and factor topography.

Background: EEG mu rhythm suppression is assessed in experiments on the execution, observation and imagination of movements. It is utilised for studying of actions, language, empathy in healthy individuals and preservation of sensorimotor system functions in patients with schizophrenia and autism spectrum disorders. While EEG alpha and mu rhythms are recorded in the same frequency range (8-13 Hz), their specification becomes a serious issue.

Sensorimotor and sensory gating in depression, anxiety, and their comorbidity.

Objectives: Abnormal attentional and cognitive processes are thought to increase the risk for depression and anxiety. To improve understanding of brain mechanisms of anxiety and depressive disorders and condition of their comorbidity, the study of early attentional processes was provided.

Methods: Participants were patients with depressive (80 s.

AUDITORY EVOKED POTENTIALS EVIDENCE FOR DIFFERENCES IN INFORMATION PROCESSING BETWEEN HIGH AND LOW HYPNOTIZABLE SUBJECTS.

N100 and P300 auditory evoked potentials in 2-stimulus oddball paradigm were analyzed in high (HH, n = 18) and low (LH, n = 15) hypnotizable participants under waking condition. LH subjects committed more errors than HH subjects. HH subjects demonstrated shorter N100 latencies at frontal electrodes and significant N100 differences between target and nontarget stimuli (higher N100 amplitude and increased latency at parietal sites to targets vs.

EEG coherence in a mental arithmetic task performance in first episode schizophrenia and schizoaffective disorder.

Objectives: To evaluate the coherence values of the cortical bands in patients with first episode schizophrenia and schizoaffective disorder during the performance of a mental arithmetic task.

Method: We analysed EEG coherence in the resting state and subsequently while counting down from 200 in steps of 7 in 32 first episode schizophrenia patients (SZ), 32 patients with first episode schizoaffective disorder (SA) and 40 healthy controls (HC).

Results: Task performance in HC is characterised by decreased coherence in the alpha bands and increased coherence in the beta 2 and gamma bands in frontal sites.

COMT Genotype and Sensory and Sensorimotor Gating in High and Low Hypnotizable Subjects.

We investigated the association between hypnotizability, COMT polymorphism, P50 suppression ratio, and prepulse inhibition of acoustic startle response (ASR) in 21 high (HH) and 19 low (LH) hypnotizable subjects. The frequency of Met/Met carriers of COMT polymorphysm was higher in HH than in LH group (33.3% versus 10.

The Study of the Antisaccade Performance and Contingent Negative Variation Characteristics in First-Episode and Chronic Schizophrenia Patients.

The study tested whether the antisaccade (AS) performance and Contingent Negative Variation (CNV) measures differed between the first-episode and chronic patients to provide the evidence of PFC progressive functional deterioration. Subjects included 15 first-episode and 20 chronic schizophrenic patients (with the duration of illness more than 5 years), and 21 control subjects. The first-episode and chronic patients had significantly elevated error percent (p < .

[Perception of Verbal Stimuli in the Norm and in Schizophrenia].

The present study investigates the early stages of selection of meaningful and meaningless verbal-in- formation in an implicit and two explicit tasks by means of the parameters of latency and amplitude of P100 EP component in healthy subjects (n = 99) and in schizophrenia patients with the first psy- chotic episode (n = 102). The obtained results indicate the disturbance of passive perception of meaningful verbal information in psychotic patients. When the instruction is presented patients re- spond similar to norm.

[The Application of Backward Masking Test for the Study of Visual Information Processing in Healthy Subjects and Schizophrenic Patients.].

The study of 14 healthy individuals and.15 schizophrenia patients was performed in condition of visual backward masking. Sensory thresholds were identified using the method of constant stimuli.

Startle Modification and P50 Gating in Schizophrenia Patients and Controls: Russian Population.

Prepulse modification of the acoustic startle response (ASR) and P50 gating are potential neurophysiological endophenotypes of schizophrenia and may be used in the construction of valid clinical biomarkers. Such approach requires a large amount of data obtained in the representative samples from different gender, socio-typological and ethnic groups, replicating studies using the similar protocols and meta-analyses. This is a replication study of ASR and the first study of P50 suppression in Russian patients with schizophrenia (n = 28) and healthy controls (n = 25).

[P100 and N170 Components of ERPs in Abstinent Cannabinoid Users during the Modified Stroop Task].

In the current work we conducted the comparative analysis of P100 and N170 components of ERPs in abstinent cannabinoid users and in healthy controls during the modified Stroop task. The latency of P100 and N170 components was shorter in the temporal, parietal and occipital areas in abstinent cannabinoid users in comparison with the control subjects. The cannabinoid group showed the decrease of P100 amplitude in the right temporal and parietal areas and the decrease of N170 amplitude in the left temporal and parietal areas.

[EEG synchronisation in autistic children. Analysis of coherency].

EEG study of 5-7 years boys with autism revealed lower values of coherence in background delta, theta and alpha bands and higher values of coherence in background beta 1, beta 2 and gamma bands. Healthy boys showed higher values of beta and gamma coherence during cognitive task. Autistic persons demonstrated higher values of theta coherence during cognitive task.

[EEG frequency and regional properties in patients with paranoid schizophrenia: effects of positive and negative symptomatology prevalence].

Objective: EEG changes in schizophrenic patients are caused by a multitude of factors related to clinical heterogeneity of the disease, current state of patients, and conducted therapy. EEG spectral analysis remains an actual methodical approach for the investigation of the neurophysiological mechanisms of the disease. The goal of the investigation was the study of frequency and regional EEG correlating with the intensity of productive and negative disorders.

The antisaccade task performance deficit and specific CNV abnormalities in patients with stereotyped paraphilia and schizophrenia.

Antisaccade task performance and mean amplitudes of slow cortical potentials (contingent negative variation--CNV) were investigated in 19 healthy volunteers, 16 schizophrenic patients (SP), and 12 patients with stereotyped form of paraphilia (PP). Compared with healthy subjects, schizophrenic and paraphilic patients committed significantly more erroneous saccades. The clear between-group CNV differences were observed during the early CNV stage that is associated with cognitive aspects of preparatory set.

The contingent negative variation laterality and dynamics in antisaccade task in normal and unmedicated schizophrenic subjects.

Contingent negative variation (CNV) topography, hemispheric asymmetry and time-course were investigated in healthy subjects and non-medicated paranoid schizophrenic patients in two antisaccade paradigms with the short (800-1000 ms) and long (1200-1400 ms) durations of the fixation period. EEG and electrooculogram (EOG) were recorded. Saccade characteristics and mean amplitudes of slow cortical potentials time-locked to peripheral target were analyzed in 23 healthy volunteers and 19 schizophrenic patients.

Waking EEG spectral power and coherence differences between high and low hypnotizable subjects.

EEG spectral power and coherence were analyzed under waking baseline condition in 19 high (HH) and 12 low (LH) hypnotizable subjects. In HH subjects, the theta1 and theta2 spectral power was higher than in LH. The major new finding of this study is that coherence between distributed brain regions was sharply elevated in HH subjects within the theta and alpha frequency bands.

The relationship between hypnotizability, internal imagery, and efficiency of neurolinguistic programming.

Subjective scoring and autonomic variables (heart rate, skin conduction span) were used to verify the reality of inner experience during recollection of emotionally neutral, positive, and negative past events in 19 high (HH) and 12 low (LH) hypnotizable subjects in hypnotic and nonhypnotic experimental sessions. Also, the influence of hypnotizability on the effectiveness of an imagery-based neurolinguistic programming (NLP) technique was evaluated. Results demonstrated that subjective scores of image vividness and emotional intensity were significantly higher in the HH subjects compared to LH in both sessions.

Chronic schizophrenics with positive symptomatology have shortened EEG microstate durations.

Objective: In young, first-episode, never-treated schizophrenics compared with controls, (a) generally shorter durations of EEG microstates were reported (Koukkou et al., Brain Topogr 6 (1994) 251; Kinoshita et al., Psychiatry Res Neuroimaging 83 (1998) 58), and (b) specifically, shorter duration of a particular class of microstates (Koenig et al.

Cortical connectivity in high frequency beta-rhythm in schizophrenics with positive and negative symptoms.

During the last decade the role of high frequency EEG activity in the 'binding phenomenon' was discovered. It was supposed that this phenomenon provided the integration between different brain structures underlying higher nervous functions and possibly even consciousness [Proc. Natl.