[The phenotype IFNy+cd69- of T-lymphocytes of umbilical blood associated with epidemiologically verified risk factors of atopy formation].

The article deals with the determination of possible role of imbalance of lymphocytes TH1/TH2 at birth in pathogenesis of atopy development in children. The subpopulation compound of umbilical blood lymphocytes was examined on sampling of 153 newborns. The following prospective monitoring was applied during first year of life.

[Place of the transplantation of the amniotic membrane in the treatment of corneal diseases concomitant with corneal neovascularization].

Published data and authors' independent observations related with the influence produced by the transplantation of the amniotic sac on corneal neovascularization are described. The epithelial-and-stromal corneal defect as well as the limbic epithelium deficit with a subsequent conjunctivization of the corneal epithelium and corneal neovascularization are one of the key mechanisms of corneal neovascularization. The amniotic sac transplantation, made for the purpose of reconstructing the eye surface, ensures the conditions for a fast recovery of the corneal epithelium and, thus, prevent the corneal neovascularization.

[Staphylococcal colonization of the oral cavity of children following an acute form of rubella infection].

The children were being observed during the course of acute rubella infection and postinfectious period. Quantitative dynamic changes in the normal microflora composition were noted weekly during the first month of the disease as well as in the beginning of the second and the third months. The amount of microorganisms registered 3 weeks and in the beginning of the second month after the onset of rubella infection differed from that in the controls.

[The characteristics of the synthesis of specific antihemagglutinins and antihemolysins in subjects inoculated with live measles vaccine in different climatic and geographical areas].

The examination of children in the Far North and moderate zones has revealed essential differences in the formation of humoral antimeasles postvaccinal immunity. After booster immunization with live measles vaccine specific anti-hemolysins are more intensively synthesized than anti-hemagglutinins under the conditions of the Far North. In the moderate climatic zone the repeated injection of live measles vaccine induces more intensive synthesis of specific anti-hemagglutinins, rather than anti-hemolysins.

[Use of beta adrenergic blockaders in the prevention of vitreous body prolapse in cataract extraction].

To prevent vitreous body prolapse in cataract extraction, intraocular pressure is reduced by means of beta-adrenoblockers instillation (timolol 0.5% solution) in the evening and 2 hours before surgery in the morning. Intraocular pressure was followed up in 59 patients with senile and 12 with complicated cataract subjected to cataract cryoextraction by the same surgeon.

[The effect of anions on spectral properties of iodopsin and native cones in the frog retina (microspectrophotometric study)].

Absorption spectra of single outer segments of the frog Rana temporaria photoreceptors were registered. Effects of nitrate and chloride ions on spectral properties of cone and rod pigments were compared. These pigments proved to differ in structure of the native photoreceptor membrane and, therefore, in effect of hydrophile environment on the chromophore centrum.

[Immune response and the dynamics of the cytolysis syndrome in viral hepatitis A and B].

Forty-nine patients with acute viral hepatitis A and B were examined for the relationship of the blood content of individual lymphocyte subpopulations at the height of the disease to subsequent duration of the cytolytic syndrome (high activity of ALT). The duration of the cytolytic syndrome associated with viral hepatitis A was reversely related to the content of B lymphocytes and when associated with viral hepatitis B to the content of T cells--immunoregulator precursors (autorosette-forming cells). In both patterns of viral hepatitis, the duration of the cytolytic syndrome did not depend on the rate of lymphocyte sensitization to the inducer antigens (HAVAg, kHBsAg).

[Characteristics of immune response regulation in viral hepatitis A and B].

In 272 patients with virus hepatitis A and B the content of theophylline-sensitive lymphocytes (T-suppressors) and theophylline-resistant lymphocytes (T-helpers) in the peripheral blood was determined. Differences in the content of T-suppressors in cases of acute virus hepatitis A and B with an equal degree of severity were revealed: at the peak of hepatitis A infection in the mild form of the disease the number of the cells was decreased, while at the peak of hepatitis B infection an increase in their number was observed in the mild and moderate forms of the disease and a decrease, in the severe form of the disease. In chronic persistent hepatitis a decrease in the content of T-suppressors and an increase in the content of T-helpers were observed, and in chronic active hepatitis (at the period of remission) and increase in the T-helpers occurred.

[Changes in the count of highly avid, thermostable blood T-cells in viral hepatitis and its outcome].

The determination of the content of thermostable T-lymphocytes in the peripheral blood in 184 patients with acute virus hepatitis, as well as at the stage of the termination of the disease, has revealed the increased number of cells belonging to this subpopulation in all the groups under study. At the acute stage of the disease a rise in the number of thermostable T-cells is directly related to the severity of the process. Of different variants of the termination of hepatitis B, the highest content of thermostable T-cells is observed in chronic active hepatitis and chronic HBsAg carriership, while in chronic persistent hepatitis the content of thermostable T-cells is considerably lower.

[Light adaptation shift in the spectral sensitivity of cones in the frog Rana temporaria].

Spectral properties of frog's "red" cones and their mass receptor potential during blue colour adaptation (370--500 nm) have been investigated. The spectral sensitivity maximum depended on the season: in September, frogs had mean lambda max of 572 +/- 4, whereas in December and January-- 553 +/- 4 nm. Low background light resulted in shift of the spectral sensitivity curve to short wavelengths.