Therapeutic potential of dopamine and serotonin in inflammation and cancer: Insights into immune regulation.

Introduction: This review explores the significant roles of neurotransmitters, focusing on dopamine and serotonin, in inflammation and cancer. These neurotransmitters are vital for neural signaling and play crucial roles in various physiological and pathological processes.

Materials And Methods: We conducted an extensive literature review, focusing on studies published between 2013 and 2024, using databases such as PubMed, Google Scholar, and Scopus.

Upright trunk and lateral or slight anterior rotation of the pelvis cause the highest proximal femur forces during sideways falls.

Whole-body models are historically developed for traffic injury prevention, and they are positioned accordingly in the standing or sitting configuration representing pedestrian or occupant postures. Those configurations are appropriate for vehicle accidents or pedestrian-vehicle accidents; however, they are uncommon body posture during a fall accident to the ground. This study aims to investigate the influence of trunk and pelvis angles on the proximal femur forces during sideways falls.

A rubberized impact absorbing pavement can reduce the head injury risk in vulnerable road users: A bicycle and a pedestrian accident case study.

Objective: Vulnerable Road Users (VRU), including pedestrians and cyclists, are generally the least protected road users and are frequently missed in the planning process of preventive measures. Rubberized asphalt mixtures were originally developed as a possible environmentally friendly solution to recycle the End-of-Life Tires while making the pavements more durable. The objective of the current study was to explore the effects of increasing the rubber content of the common rubberized asphalt mixtures in reducing the head injuries risk for VRUs.

Influence of nonlinear soft tissue modeling on the external and internal forces during lateral hip impacts.

Soft tissues in the hip region, which are typically considered the natural shock-absorbers during falls, attenuate the applied forces to the underlying hard tissue. The soft tissue thickness is, therefore, a significant parameter in the force attenuation. Another factor that could affect the assessment of the force attenuation in numerical simulations is the choice of constitutive model and material parameters for the soft tissue.

Effects of pulsatile perfusion during cardiopulmonary bypass on biochemical markers and kidney function in patients undergoing cardiac surgeries.

For several years there is no conclusive guideline on the effectiveness of pulsatile or non-pulsatile perfusion during cardiopulmonary bypass (CPB) in patients undergoing cardiac surgeries. In this study, we evaluated the effect of pulsatile versus continuous perfusion on the myocardial release of the cardiac biochemical markers including, creatine phosphokinase (CPK), cardiac creatine kinase (CK-MB), and lactate dehydrogenase (LDH), and also kidney function tests including: blood urea nitrogen test (BUN) and creatinine test (Cr) in patients that underwent both pulsatile and non-pulsatile methods before and after heart surgeries. A total of 80 patients were enrolled in this study, 40 patients in each pulsatile and non-pulsatile group.