Publications by authors named "Noura Mohammed Alshiban"
Article Synopsis
- The study investigated the health benefits of Ramadan fasting (RFM) in both obese and non-obese rats, focusing on its effects on longevity and metabolic biomarkers.
- Rats were divided into groups fed standard or high-fat diets over 12 weeks, with some undergoing fasting and exercise, while others were given glucose.
- Results showed that RFM led to lower levels of certain pro-inflammatory and metabolic markers, improved anti-inflammatory and antioxidant levels, and boosted gene expression linked to longevity, indicating that RFM has potential health advantages, especially for those on a high-fat diet.
Glibenclamide (GB), oral antidiabetic sulfonylurea, is used in the management of diabetes mellitus type II. It suffers from low bioavailability due to low water solubility. This work aimed to enhance the dissolution of GB by formulating the drug as a proniosomes which then improves the pharmacological effect.
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