Publications by authors named "Noura Kabbani"

Introduction: Optimal counseling of women for vaginal breech birth requires consideration of both established and emerging risk factors for adverse perinatal outcomes. Currently, rising prevalences of maternal obesity and impaired glucose tolerance challenge obstetric care. We aimed to investigate the effects of these parameters on the outcome of vaginal breech birth to improve counseling practices.

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Article Synopsis
  • The study aims to create prediction models for intrapartum cesarean sections during vaginal breech births, focusing on nulliparous (first-time mothers) and multiparous (previously giving birth) women.
  • Two prediction models were developed for each group, with the nulliparous model having an AUC (Area Under Curve) of 0.67 and the multiparous model showing better performance at 0.77, indicating higher accuracy.
  • Key risk factors identified include epidural analgesia, maternal height, birth weight, and abdominal circumference, with a significant finding that certain factors only influence cesarean outcomes when birth weights exceed 3.8 kg or abdominal circumference is above 34 cm.
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Transforming growth factor beta-1 (TGFβ1) is an adipokine secreted from adipose tissue, placental tissue and immune cells with a role in cell proliferation, cell apoptosis and angiogenic proliferation. The role of TGFβ1 in pregnancy and child growth and the source of cord TGFβ1 are yet unknown. In this study, we sought to clarify the correlation of TGFβ1 levels with parameters of intrauterine growth and child growth during the first year of life, and to determine whether their source is primarily of fetal or maternal origin.

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Adipokines are signaling proteins involved in metabolic, endocrinological, vascular and immunogenic processes. Associations of various adipokines with not only insulin resistance but also with increased insulin sensitivity, increased systolic blood pressure, and atherosclerosis highlight the significance of adipokines in several components of metabolic syndrome and metabolic diseases in general. As pregnancy presents a unique metabolic state, the role of adipokines in pregnancy, and even in various pregnancy complications, appears to be key to elucidating these metabolic processes.

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