Publications by authors named "Noura Chelali"
Neonatal growth and regeneration of beta-cells are regulated by the Wnt/beta-catenin signaling in normal and diabetic rats.
Am J Physiol Endocrinol Metab
February 2010
Article Synopsis
- Scientists studied how a signaling pathway called Wnt/beta-catenin affects the growth and repair of beta cells, which are important for insulin production, in healthy and diabetic rats.
- They used special techniques to either turn off or activate this signaling pathway and found that turning it off reduced beta-cell growth, while activating it helped diabetic rats grow more beta cells.
- The results suggest that improving this Wnt signaling could help develop new treatments for diabetes by encouraging better beta-cell regeneration.