Exploring the wound-healing and antimicrobial potential of Dittrichia viscosa L lipidic extract: Chemical composition and in vivo evaluation.

Dittrichia viscosa belongs to the Dittrichia genus, it grows abundantly in the east and northeast of Morocco, and traditionally its fresh leaves are crushed and given for topical application after burns, wounds, and infections. In this study, we examine the wound-healing activity of Dittrichia viscosa lipidic extract in vivo, assess its anti-microbial effect, and explore the specific compounds that contribute to these effects. To assess the effectiveness of wound healing, a burn-induced wound model was employed in Wistar rats, and the levels of hydroxyproline as well as histopathological changes in the skin tissues were evaluated.