Optimizing dosimetric accuracy in radioembolization: comparative effectiveness of SPECT/CT, planar imaging, and PET/CT for lung shunt fraction assessment.

Background: In radioembolization therapy for hepatic malignancies, the accurate estimation of lung shunt fraction (LSF) is crucial to minimize the risk of radiation-induced pneumonitis and fibrosis due to hepatopulmonary shunting of yttrium-90 (90Y)-microspheres. This study aimed to compare the accuracy and precision of LSF estimation using technetium-99m macroaggregated albumin single photon emission computed tomography ([99mTc]Tc-MAA SPECT) LSF, [99mTc]Tc-MAA planar LSF, and 90Y PET LSF in patients undergoing 90Y-radioembolization.

Material And Methods: A retrospective study was conducted involving 15 patients diagnosed with hepatocellular carcinoma (HCC) or liver metastases and planned to undergo transarterial radioembolization with 90Y SirSpheres after multidisplinary team discussion.

ASSESSMENT OF OCCUPATIONAL RADIATION DOSES IN DIFFERENT DIAGNOSTIC, INTERVENTIONAL AND THERAPEUTIC RADIOLOGY AND MOLECULAR IMAGING SERVICES IN OMAN.

This study aimed at assessing occupational radiation doses in different diagnostic, interventional and therapeutic services. Personal dose equivalent, Hp(10), of 116 medical radiation workers, all with 3 y of dose records (2015-18), were collected from the TLD dosimetry service at the Sultan Qaboos University Hospital-a 700-bed tertiary care teaching hospital in Oman. The doses were measured using calibrated thermo-luminescence dosemeters (TLD-100 (LiF:Mg,Ti)).