Publications by authors named "Nouf T Al-Damry"
Biomed Pharmacother
November 2018
Article Synopsis
- The study investigates how sitagliptin, a diabetes medication, protects against heart cell death in diabetic cardiomyopathy (DCM) by influencing specific survival and apoptotic kinases.
- Diabetic rats treated with sitagliptin showed improved heart health markers and reduced signs of heart damage compared to untreated diabetic rats.
- Sitagliptin's benefits are linked to its ability to enhance the activity of survival kinases (AMPK and Akt) and decrease the activation of apoptotic kinases (GSK-3β and p38MAPK), potentially offering a therapeutic strategy for DCM management.
