Optimization of HIV drugs through MCDM technique Analytic Hierarchy Process(AHP).

Topological indices are crucial tools for predicting the physicochemical and biological features of different drugs. They are numerical values obtained from the structure of chemical molecules. These indices, particularly the degree-based TIs are a useful tools for evaluating the connection between a compound's structure and its attributes.

Clinical Characteristics and Outcomes of Deep Vein Thrombosis in Relation to Location: A Retrospective Analysis Study.

Deep vein thrombosis (DVT) is a leading cause of death disability. DVT can be classified based on the location and extent of the clot into isolated distal DVT (iDDVT), isolated proximal DVT (iPDVT), or mixed DVT. The aim of this study is to explore the baseline characteristics and clinical outcomes of patients with different types of DVT.

A computational approach to drug design for multiple sclerosis via QSPR modeling, chemical graph theory, and multi-criteria decision analysis.

Multiple sclerosis (MS) is a complex autoimmune disease of the central nervous system with an unknown etiology. While disease-modifying therapies can slow progression, there is a need for more effective treatments. Quantitative structure-activity relationship (QSAR) modeling using topological indices derived from chemical graph theory is a promising approach to rationally design new drugs for MS.

Hybrid Functional Near-Infrared Spectroscopy System and Electromyography for Prosthetic Knee Control.

The increasing number of individuals with limb loss worldwide highlights the need for advancements in prosthetic knee technology. To improve control and quality of life, integrating brain-computer communication with motor imagery offers a promising solution. This study introduces a hybrid system that combines electromyography (EMG) and functional near-infrared spectroscopy (fNIRS) to address these limitations and enhance the control of knee movements for individuals with above-knee amputations.

Factors Associated With Turnover Intention Among Healthcare Providers in Saudi Arabia: A Comprehensive Review.

Turnover has a negative impact and can harm businesses, specifically the organizational structure and service delivery. The purpose of this review is to provide policymakers, healthcare administrators, and stakeholders in Saudi Arabia with approaches and strategies for reducing turnover and improving provider retention by synthesizing existing literature and identifying the key variables influencing turnover intention. This study conducted a comprehensive literature review to explore numerous variables associated with medical professional turnover intentions in Saudi Arabia from 2016 to 2024.

Recent progress on smart lower prosthetic limbs: a comprehensive review on using EEG and fNIRS devices in rehabilitation.

The global rise in lower limb amputation cases necessitates advancements in prosthetic limb technology to enhance the quality of life for affected patients. This review paper explores recent advancements in the integration of EEG and fNIRS modalities for smart lower prosthetic limbs for rehabilitation applications. The paper synthesizes current research progress, focusing on the synergy between brain-computer interfaces and neuroimaging technologies to enhance the functionality and user experience of lower limb prosthetics.

Statistical analysis in cellular systems for channel capacity improvement with dynamic pilots across different angles users.

Accurate channel state information (CSI) is crucial for optimizing wireless communication systems. In scenarios with varying user-to-base station angles, the angle-dependent coherence time impacts conventional pilot strategies. Due to small angles, the coherence time of the user decreases dramatically because of doppler shift, which causes an increase in the number of pilots.

A novel simulation-based analysis of a stochastic HIV model with the time delay using high order spectral collocation technique.

The economic impact of Human Immunodeficiency Virus (HIV) goes beyond individual levels and it has a significant influence on communities and nations worldwide. Studying the transmission patterns in HIV dynamics is crucial for understanding the tracking behavior and informing policymakers about the possible control of this viral infection. Various approaches have been adopted to explore how the virus interacts with the immune system.

Juvenile Dermatomyositis Presenting As Generalized Poikiloderma: A Case Report.

Juvenile dermatomyositis (JDM) is a chronic autoimmune inflammatory disorder and is considered the most common form of idiopathic inflammatory myopathies. JDM primarily affects the skin and the skeletal muscles. Characteristic signs and symptoms include Gottron papules, heliotrope rash, calcinosis cutis, and symmetrical proximal muscle weakness.

Designing a Band for Vehicles' Drivers Induced by Ultraviolet and Infrared Radiations.

Background: Solar radiations that reach the Earth can be divided into ultraviolet, visible light, and infrared. Overexposure to these radiations can facilitate adverse skin diseases such as sunburn, skin cancer, and photoaging. People who drive vehicles for an extended period are likely to develop skin cancer in the exposed body area.

Body mass index among elderly population and its association with neurological and musculoskeletal diseases in Aseer, Saudi Arabia.

Introduction: An increase in BMI in the elderly may reduce life expectancy and increase the risk of death, cardiovascular disease, and metabolic syndrome. Frailty index, body weight, and pain levels all seem to be linked. Excessively low or high body weight may cause muscle weakness and decrease physical activity, placing the elderly at risk for frailty.

Biocompatibility and antioxidant activity of a novel carrageenan based injectable hydrogel scaffold incorporated with Cissus quadrangularis: an in vitro study.

Background: Over the past years, polysaccharide-based scaffolds have emerged as the most promising material for tissue engineering. In the present study, carrageenan, an injectable scaffold has been used owing to its advantage and superior property. Cissus quadrangularis, a natural agent was incorporated into the carrageenan scaffold.

Cutaneous Features of Anti-MDA-5 Antibody-Positive Amyopathic Dermatomyositis in a Sudanese Patient.

Clinically amyopathic dermatomyositis (CADM) is a rare form of DM characterized by unique cutaneous and pulmonary features with no muscle involvement. A subset of patients with CADM has a specific antibody known as anti-melanoma differentiation-associated protein 5 (MDA5). The systemic associations of anti-MDA-5 CADM warrant an early recognition and management to prevent fetal sequelae.

Vertical Load and Torque during Postspace Preparation and Their Influence on Microcrack Development.

Purpose: To investigate, in vitro, the magnitudes of vertical load and torque generated during post space preparation of root canal treated teeth and their influence on microcrack development.

Materials And Methods: Forty extracted premolars with single canals were decoronated. The roots were prepared using ProTaper Next system (Dentsply Sirona) to X3 file, obturated, and provisionalized.

Oral and oropharyngeal cancer: Knowledge, attitude and practices among medical and dental practitioners.

Background: Oral and oropharyngeal cancer are significant health problems. They are both life-threatening conditions usually diagnosed at an advanced stage causing survival rates to decline.

Aim: To assess and compare practices, knowledge and attitude regarding oral and oropharyngeal cancer between dental and medical practitioners.