Publications by authors named "Nottin S"

Purpose: The present study examined the influence of endurance training on the morphological and functional heart adaptations in young athletes throughout a longitudinal 9-month follow-up period during the adolescent peak height velocity (PHV).

Methods: Thirty-six 13- to 15-year-old males (twenty-three triathletes and thirteen untrained peers) were evaluated before and after a 9-month period during PHV. Maximal oxygen uptake ( ) and power at were assessed during incremental cycling test.

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  • Prolonged strenuous exercise can temporarily impair cardiac function and lead to pulmonary issues like bronchoconstriction, dynamic hyperinflation, and reduced gas exchange capacity.
  • The study assessed 60 male triathletes before and after a long-distance race to compare cardiac function in those with and without exercise-induced pulmonary dysfunctions.
  • Post-race findings showed declines in both systolic and diastolic functions across all groups, but those with diffusion impairment had more significant decreases in cardiac work and specific heart metrics.
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Even if more and more women are involved in strength-training (ST) programs in fitness centers, studies on strength gain, body composition, and cardiac remodeling were mainly conducted in men and whether they are similar in women remains to be explored. In this context, the aim of our study was to assess the effect of a supervised ST program on strength gains, body composition, and cardiac remodeling in previously untrained women and men. 17 healthy and previously untrained young women and 17 young men participated in a supervised 16-week ST program built according to the recommendation of the American College of Sports Medicine in terms of intensity, and strictly using similar volume and intensity in both groups.

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Background: Neuromuscular function is considered as a determinant factor of endurance performance during adulthood. However, whether endurance training triggers further neuromuscular adaptations exceeding those of growth and maturation alone over the rapid adolescent growth period is yet to be determined.

Objective: The present study investigated the concurrent role of growth, maturation, and endurance training on neuromuscular function through a 9-month training period in adolescent triathletes.

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  • - Early differences in neuromuscular function were found between strength-trained (wrestling) and endurance-trained (triathlon) adolescent athletes, highlighting that such variations can emerge by early adolescence.
  • - The study involved 23 triathletes, 12 wrestlers, and 12 untrained male adolescents, measuring knee extensor torque and muscle activation through various techniques like isometric contraction and EMG.
  • - Results indicated that wrestlers had higher knee extensor torque and specific muscle architectural advantages compared to triathletes and untrained individuals, suggesting that strength training could lead to distinct neuromuscular characteristics even in young athletes.
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  • Left atrial (LA) function is crucial for heart performance, particularly in individuals undergoing hemodialysis (HD), but how it changes during HD is not well-studied.
  • A trial involving 56 HD patients examined the impact of a 30-minute aerobic exercise session (intradialytic exercise, IDE) during HD, revealing that IDE significantly prevented the decline in LA function.
  • While IDE showed positive effects on LA and left ventricular function, these benefits diminished in patients with enlarged LA, indicating a need for further research into long-term IDE effects.
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Background: Myocardial work (MW) is a new echocardiographic tool with a high sensitivity to detect early and subtle alterations of myocardial function. We aimed to evaluate the late effects of anthracyclines by assessing the global and segmental MW and intraventricular mechanical dispersion from speckle tracking echocardiography in childhood lymphoma survivors (CLS).

Methods: Thirty-one young adults including CLS and age-matched healthy controls were enrolled.

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Background And Aims: In adolescents with obesity, a left atrial (LA) enlargement has been reported. However, data regarding its function and its stiffness are missing. The aim of this study was to describe LA morphology and function, using speckle-tracking echocardiography (STE) and to explore their potential determinants in adolescents with obesity.

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Background: Adolescent weight disorders ranging from anorexia nervosa (AN) to obesity (OB) can impact the heart by causing opposite alterations in its morphology, suggesting a direct impact of body mass index (BMI) on the heart. Cardiac function is relatively preserved as assessed by standard echocardiography. However, few studies have used 2D speckle-tracking echocardiography (2D-STE), which can detect subtle alterations of left ventricular (LV) function by evaluating deformations.

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Background And Aims: Hypovitaminosis D is associated with the risk of diabetic complications. Its role in diabetic-related cardiac abnormalities remain poorly understood. We aimed therefore to evaluate the effect of vitamin D deficiency and supplementation on early left ventricular (LV) dysfunction in vitamin D deficient patients with uncomplicated T2D.

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  • Hemodialysis (HD) can cause acute dysfunction in the left ventricle (LV), leading to myocardial stunning due to inadequate blood flow, and exercise during dialysis may help stabilize hemodynamics and blood pressure.* -
  • A study involving 60 patients with end-stage kidney disease (ESKD) revealed that acute intradialytic exercise (IDE) significantly improved LV function, beyond just changes in cardiac loading conditions.* -
  • These results suggest that incorporating IDE into regular HD procedures could reduce the risk of heart failure and other cardiac issues in ESKD patients.*
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Objective: The interplay between metabolic syndrome (MS) and type 2 diabetes (T2D) on regional myocardial mechanics and the potential additional effects of their combination remain poorly understood. In this context, we evaluated left ventricular (LV) torsion and linear deformation at rest and under dobutamine (DB) stress in patients with T2D, MS or both.

Methods: Thirty-nine T2D patients without MS (T2D), 37 MS patients free from T2D (MS), 44 patients with both T2D and MS (T2D-MS group) and 38 healthy patients (control group) were prospectively recruited.

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Background: Strength-trained athletes using anabolic androgenic steroids (AAS) have left ventricular (LV) hypertrophy and myocardial fibrosis that can lead to sudden cardiac death. A similar feature was described in athletes with hypertrophic cardiomyopathy (HCM), which complicates the diagnosis for clinicians. In this context, we aimed to compare the LV function of the 2 populations by measuring global and regional strain and myocardial work using speckle-tracking imaging.

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We investigated the acute cardiac consequences of a long-duration (>5 h) adventure race in adolescent athletes from evaluations of left ventricular (LV) strains and myocardial work. Twenty trained male adolescents (i.e.

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Unlabelled: Purpose: The aim of the present study was to assess left ventricular (LV) morphological and regional functional adaptations in backs and forwards elite rugby union (RU) players.

Methods: Thirty-nine elite male RU players and twenty sedentary controls have been examined using resting echocardiography. RU players were divided into two groups, forwards ( = 22) and backs ( = 17).

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Cardiovascular alterations in anorexia nervosa (AN) adolescents include bradycardia and decreased systolic blood pressure and left ventricular mass. However, their determinants remain poorly understood. We assessed the associations between morphological and functional left ventricular (LV) remodeling, autonomic control by heart rate variability (HRV) analysis, thyroid hormones and brain natriuretic peptide (BNP) levels in AN female adolescents without or with weight recovery (WR).

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  • The study investigates the biochemical effects of a long adventure race (>5h) on hydration, blood electrolytes, and kidney function in adolescent athletes aged 14 to 17.
  • Twenty male participants completed a 68.5 km race while monitoring their fluid intake and undergoing blood tests before, after, and 24 hours post-race.
  • Results showed stable blood sodium levels and no significant kidney function changes, indicating the race did not lead to dehydration or harmful effects on kidney function in the participants.
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Purpose: Despite potential severe cardiac side effects, anabolic androgenic steroids (AAS) are increasingly used by strength athletes. However, previous echocardiographic studies focused on the left ventricular (LV) strains but did not assess LV twist and untwist mechanics. Moreover, left atrial (LA) function has been often neglected, and its stiffness, an important determinant of LA reservoir function, has never been challenged.

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The present study investigated the acute effects of a mixed-modality, long-duration adventure race on pulmonary function in adolescent athletes. Twenty male adolescents aged 14 to 17 years volunteered to participate in a wilderness adventure race of 68.5-km.

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Background: Anorexia nervosa (AN) and obesity (OB) lead to changes in SBP (i.e., loading conditions) that may affect left ventricular (LV) myocardial work (MW).

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  • Endurance-trained athletes, like cyclists, have a quicker increase in oxygen use when they start exercising compared to people who don’t exercise regularly.
  • The study compared the heart's performance of trained cyclists and untrained participants during exercise to see how well their hearts responded.
  • Results showed that trained cyclists had faster heart filling and twisting actions, making their hearts pump more efficiently when they started to exercise.
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Left ventricular (LV) remodeling, characterized by increased LV hypertrophy and depressed systolic and diastolic function, is observed in strength-trained athletes who use anabolic-androgenic steroids (AAS). Previous studies suggested a pathological remodeling with an increase in cardiac fibrosis in these athletes, which could promote intraventricular dyssynchrony. In this context, this study evaluated LV dyssynchrony in strength-trained athletes using AAS, hypothesizing that the use of AAS would lead to an increase in post-systolic shortening.

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Purpose: To characterize the acute effects of a long-duration adventure race on knee extensor (KE) fatigue and the knee functional ratio in adolescent athletes.

Methods: Twenty trained male adolescents (aged 14-17 y) performed an adventure race of 68.5 km.

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The purpose of this study is to evaluate the influence of competition level on running patterns for five playing position in the most successful 2014-2015 European rugby union team. Seventeen French rugby union championship and seven European rugby Champions Cup games were analysed. Global positioning system (sampling: 10 Hz) were used to determine high-speed movements, high-intensity accelerations, repeated high-intensity efforts and high-intensity micro-movements characteristics for five positional groups.

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