Glucagon response to oral glucose challenge in type 1 diabetes: lack of impact of euglycemia.

OBJECTIVE Previous studies have demonstrated aberrant glucagon physiology in the setting of type 1 diabetes (T1D) but have not addressed the potential impact of ambient glycemia on this glucagon response. Thus, our objective was to evaluate the impact of euglycemia versus hyperglycemia on the glucagon response to an oral glucose challenge in T1D. RESEARCH DESIGN AND METHODS Ten adults with T1D (mean age 56.

Adenoid cystic carcinoma of the airway: thirty-two-year experience.

Methods: We have reviewed our experience in 38 patients with adenoid cystic carcinoma of the upper airway seen between 1963 and 1995. The mean age was 44.8 years (15 to 80 years) with a male/female ratio of 1:1.

A study of cell membrane structure.

Neoplastic transformation has been associated with a variety of structural changes, among which are changes in membrane carbohydrates. Not much is known, though, e.g.

Lectin binding characteristics of laryngeal cancer.

Previous reports have shown specific binding characteristics of peanut lectin to a variety of lymphatic and epithelial tumors. This study demonstrates the presence of lectin binding sites on cell membrane of laryngeal cancer cells, but not on adjacent normal epithelial linings. It also demonstrates the presence of glycoconjugates responsible for lectin adherence in fetal larynges.

Paraganglioma of the larynx.

A patient with a laryngeal paraganglioma is presented in which overtly malignant behavior occurred despite a four-year period of symptoms prior to diagnosis. A review of the world literature reveals 52 reported cases of laryngeal paragangliomas. The incidence of malignancy in these neoplasms is often underestimated, as at least 25% of reported cases exhibited a clinically malignant natural history.

Eccrine hidrocystoma of the external ear canal: a case report.

Eccrine hidrocystomas are essentially sweat gland retention cysts located in the dermis. Clinically, an eccrine hidrocystoma presents as a small, translucent cystic swelling (often having a bluish hue), and measuring from 1 to 3 mm in diameter. The clinical and histopathological features of an eccrine hidrocystoma of the external auditory canal are presented, and the morphologic differences between an eccrine and an apocrine hidrocystoma are discussed.

Cavernous hemangioma of the external ear canal.

Cavernous hemangiomas are benign tumors of blood vessel origin. Cavernous hemangiomas arising from the tympanic membrane with or without involvement of the skin of the deep external auditory canal may occur in rare cases. In this paper, the clinical and pathological findings in the first recorded case of a patient with a cavernous hemangioma arising from the skin of the deep external canal with no involvement of the tympanic membrane are presented.