First Observation of Neutral Bremsstrahlung Electroluminescence in Liquid Argon.

A recent discovery of additional mechanism of electroluminescence (EL) in noble gases due to the neutral bremsstrahlung (NBrS) effect led to a prediction that NBrS EL should be present in noble liquids as well. A theoretical model of NBrS EL in noble liquids was developed accordingly in the frameworks of Cohen-Lekner and Atrazhev. In this work, we confirm this prediction: For the first time, visible-range EL has been observed in liquid argon at electric fields reaching 90  kV/cm, using gas electron multiplier (GEM) and thick GEM structures.

Polysaccharides Are Effective Inhibitors of Natural Gas Hydrate Formation.

This review covers the types and applications of chemical inhibitors of gas hydrate formation in the oil and gas industry. The main directions of the development of new types of highly effective and environmentally safe "green" kinetic hydrate inhibitors (KHIs) based on biopolymers are analyzed. The structure, physicochemical properties, efficiency of gas hydrate formation inhibition, and commercial prospects of polysaccharides in preventing and controlling the formation of gas hydrates are considered.

Polysaccharides as Effective and Environmentally Friendly Inhibitors of Scale Deposition from Aqueous Solutions in Technological Processes.

In this paper, we consider natural and modified polysaccharides for use as active ingredients in scale deposition inhibitors to prevent the formation of scale in oil production equipment, heat exchange equipment, and water supply systems. Modified and functionalized polysaccharides with a strong ability to inhibit the formation of deposits of typical scale, such as carbonates and sulfates of alkaline earth elements found in technological processes, are described. This review discusses the mechanisms of the inhibition of crystallization using polysaccharides, and the various methodological aspects of evaluating their effectiveness are considered.

Effect of Gd, La, Lu Co-Doping on the Morphology and Luminescent Properties of NaYF:Sm Phosphors.

The series of luminescent NaYF:Sm nano- and microcrystalline materials co-doped by La, Gd, and Lu ions were synthesized by hydrothermal method using rare earth chlorides as the precursors and citric acid as a stabilizing agent. The phase composition of synthesized compounds was studied by PXRD. All synthesized materials except ones with high La content (where LaF is formed) have a β-NaYF crystalline phase.

Brightly Luminescent (TbLu)bdc·nHO MOFs: Effect of Synthesis Conditions on Structure and Luminescent Properties.

Luminescent, heterometallic terbium(III)-lutetium(III) terephthalate metal-organic frameworks (MOFs) were synthesized via direct reaction between aqueous solutions of disodium terephthalate and nitrates of corresponding lanthanides by using two methods: synthesis from diluted and concentrated solutions. For (TbLu)bdc·nHO MOFs (bdc = 1,4-benzenedicarboxylate) containing more than 30 at. % of Tb, only one crystalline phase was formed: Lnbdc·4HO.

Heterometallic Europium(III)-Lutetium(III) Terephthalates as Bright Luminescent Antenna MOFs.

A new series of luminescent heterometallic europium(III)-lutetium(III) terephthalate metal-organic frameworks, namely (EuLu)bdc·nHO, was synthesized using a direct reaction in a water solution. At the Eu concentration of 1-40 at %, the MOFs were formed as a binary mixture of the (EuLu)bdc and (EuLu)bdc·4HO crystalline phases, where the Lnbdc·4HO crystalline phase was enriched by europium(III) ions. At an Eu concentration of more than 40 at %, only one crystalline phase was formed: (EuLu)bdc·4HO.

Lanthanide-Ion-Doping Effect on the Morphology and the Structure of NaYF:Ln Nanoparticles.

Two series of β-NaYF:Ln nanoparticles (Ln = La-Nd, Sm-Lu) containing 20 at. % and 40 at. % of Ln with well-defined morphology and size were synthesized via a facile citric-acid-assisted hydrothermal method using rare-earth chlorides as the precursors.

Ultrasound-Assisted Synthesis of Luminescent Micro- and Nanocrystalline Eu-Based MOFs as Luminescent Probes for Heavy Metal Ions.

The luminescent coarse-, micro- and nanocrystalline europium(III) terephthalate tetrahydrate (Eubdc·4HO) metal-organic frameworks were synthesized by the ultrasound-assisted wet-chemical method. Electron micrographs show that the europium(III) terephthalate microparticles are 7 μm long leaf-like plates. According to the dynamic light scattering technique, the average size of the Eubdc·4HO nanoparticles is equal to about 8 ± 2 nm.

Live births and maintenance with levonorgestrel IUD improve disease-free survival after fertility-sparing treatment of atypical hyperplasia and early endometrial cancer.

Objective: Our objectives were to (1) compare different regimens of hormonal therapy (HT) in young women with atypical endometrial hyperplasia (AEH) and early endometrial cancer (EC), (2) assess reproductive and oncologic outcomes and (3) explore possible predictors of complete response (CR) and disease free survival (DFS).

Methods: Reproductive age women with AEH and Grade 1-2 endometrioid EC with no or minimal myometrial invasion on MRI treated with different regimens of HT were prospectively analyzed. Treatment protocols included levonorgestrel intrauterine device (LNG IUD), gonadotropin-releasing hormone agonist (aGnRH) or high-dose oral medroxyprogesteron acetate (MPA) separately and in combinations.

[Efficacy and safety of new oral anticoagulants as part of triple antithrombotic therapy in patients with atrial fibrillation and acute coronary syndrome. Data from an observational study].

Aim To study efficacy and safety of a triple antithrombotic therapy with direct oral anticoagulants (DOAC) versus warfarin in patients with atrial fibrillation after acute coronary syndrome, for 12 months following discharge from the hospital.Materials and methods This single-site cohort, prospective, observational study performed at the Regional Vascular Center 2 of the N.A.

[Atrial Flutter: up-to-date Problem Evaluation with Clinical Positions].

The review provides current ideas about the etiology and prevalence of atrial flutter (AF), mechanism and substrate of arrhythmogenesis, and principles of clinical and electrophysiological classification of this arrhythmia. Methods for conservative and surgical treatments of AF, including their comparative aspect, are described in detail. The review presented recent data on efficacy and potential risks of different approaches to reversing the arrhythmia.

[Multifactorial Prognostication of the Development of Stent Thrombosis in Patients with Acute Coronary Syndrome after Percutaneous Coronary Intervention on the background of Dual Antiplatelet Therapy].

Aim: to identify predictors of stent thrombosis in patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI) for 12 months by creating a miathematical logistic regression model to optimize rehabilitation, secondary prevention of ischemic events in the first year after ACS, as well as a personalized approach to treatment.

Materials And Methods: The analysis used data from the hospital register, which contained information on all PCIs, performed in the Semashko hospital between September 2016 and August 2018 (2378 patients). For this study we selected a sample of 183 ACS patients (146 men and 37 women) after PCI: 25 with definite stent thrombosis confirmed by repeated coronary angiography (CAG) (the main study group), and 158 without developing definite stent thrombosis (the comparison group) according to the observation for 12 months.

[Double antiplatelet therapy in patients with acute coronary syndrome after percutaneous coronary intervention: individual efficacy and hemorrhagic safety of P2Y12 blockers of ticagrelor and clopidogrel in actual clinical practice].

Aim: To study the comparative efficacy and safety of clopidogrel and ticagrelor in the "double" antiplatelet therapy (DATT) in patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI) in the early and late periods in real clinical practice, and to assess adherence to treatment.

Materials And Methods: The study included 109 patients with ACS, who underwent PCI. Patients were divided into two groups: the 1st group (n=57) - received ticagrelor and the 2nd group (n = 52) - received clopidogrel in the DATT for 12 months.

[Issues of antithrombotic therapy in ACS patients with atrial fibrillation].

The review analyzed current ideas on prevalence and clinical significance of atrial fibrillation following acute coronary syndrome; described modern approaches to administration of antithrombotic therapy; and addressed available clinical studies on the treatment with warfarin and new oral anticoagulants as a part of combination antithrombotic therapy in patients with atrial fibrillation and acute coronary syndrome.

[Major predictors of stent thrombosis in patients with acute coronary syndrome following transcutaneous coronary intervention who received different double antiplatelet therapy].

The review analyzes the reports addressing from different standpoints the issue of stent thrombosis and its major predictors in patients with acute coronary syndrome following transcutaneous coronary interventions. The review focuses on comparative efficacy and safety of ticagrelor and clopidogrel and the effect of double antiplatelet therapy on stent thrombosis. The issue of patients' compliance with double antiplatelet therapy is also discussed.

Causes of non-Kolmogorov turbulence in the atmosphere.

In the present work, we briefly describe a model for atmospheric turbulence energy on the basis of experimental data obtained in Siberia. A series of new studies is considered and the results of our long-term experimental observations are summarized. The results of these studies form the basis for an explanation of some effects in interactions between optical waves and atmospheric turbulence.

Comparison of Kolmogorov's and coherent turbulence.

Features of optical wave fluctuations while propagating through a randomly inhomogeneous turbulent medium with a finite outer scale are considered, including conditions when areas with dominating influence of one large-scale coherent structure are observed in the atmosphere, for which the spectrum of atmospheric turbulence can differ significantly from the Kolmogorov model spectrum. Using an approximate model of the spectrum for coherent turbulence, described earlier in our works, the variance of jitter of an optical image is calculated (under the applicability condition for the smooth perturbation method). The comparison of these equations with known similar equations for Kolmogorov turbulence has shown that the variance of fluctuations is significantly weaker in coherent turbulence than in the Kolmogorov theory under similar conditions.

Features of optical image jitter in a random medium with a finite outer scale.

For more than 40 years, we have studied the effect of the low-frequency spectral range of atmospheric turbulence on optical characteristics. We also have looked at the influence of the turbulence models as well as an outer scale of turbulence on the parameters of telescopes and systems of laser beam formations. This question is important mainly for ground-based astronomy.

Information system for the implementation of individual rehabilitation programs for persons with disabilities in Nizhny Novgorod region.

In December 2011, the first phase of the project aimed at developing an information system for the implementation of individual rehabilitation programs for persons with disabilities was finished in Nizhny Novgorod region of Russia. It included the installation of 40 workstations in the Ministry for Social Policy and 8 institutions of Nizhny Novgorod region. Accumulated data were moved to a new information system based on a distributed database.

Relationship between the expression of VEGF signal components and matrix metalloproteinases in ovarian tumors.

The content of vascular endothelium growth factor is significantly increased, while the level of matrix metalloproteinase-2 is 2-fold reduced in ovarian cancer tissue compared to benign tumors. A trend to an increase in the levels of matrix metalloproteinases 7 and 9 and reduction of vascular endothelial growth factor type 2 receptors in tumor tissue was also detected. A highly significant negative correlation between the levels of vascular endothelial growth factor and matrix metalloproteinase 2 and positive correlations between vascular endothelial growth factor and matrix metalloproteinase 7, vascular endothelial growth factor and matrix metalloproteinase 9, matrix metalloproteinase 2 and vascular endothelial growth factor type 2 receptors were revealed.

Occurrence of hydrodynamic cavitation.

In this paper, the conditions under which cavitation (or liquid film rupture) can or cannot occur in thin layers of moving liquid are derived for three typical cases. At the same time, expressions depending on geometrical and movement parameters, where cavitation might start, are given. The results are obtained using simple engineering terms, which can be used in cases whether it is necessary to avoid cavitation or to induce it.

Non-Peutz-Jeghers syndrome associated ovarian sex cord tumor with annular tubules: a case report.

Objective: Sex cord tumors with annular tubules (SCTAT) are a rare subtype of sex cord stromal tumor of the ovary. An evidence-based management plan with follow-up evaluations is difficult to outline because of the rarity of these tumors. We describe the case of a premenarcheal patient with a SCTAT.

Predictors of recurrence of ovarian granulosa cell tumors.

Objective: The prognosis of granulosa cell tumors (GCTs) is overall favorable, but a proportion of patients will experience recurrence. We report one of the largest series of patients with GCT for whom clinical, morphologic, and immunohistochemical markers have been assessed for their roles as predictors of recurrence.

Methods: Patients with the diagnosis of GCT were identified at 2 hospitals from 1974 to 2004; a detailed chart analysis was performed.

Validation of serum biomarkers for detection of early-stage ovarian cancer.

Objective: Ovarian cancer has the highest mortality of all the gynecologic malignancies with most patients diagnosed at late stages. Serum CA-125 is elevated in only half of patients with stages I-II. We identified 3 serum proteins (apolipoprotein A-1, transthyretin, and transferrin) for the detection of ovarian cancer and reported them combined with CA-125 to effectively detect early-stage mucinous tumors.

[The condition of vascular-thrombocyte hemostasis in the elderly with arterial hypertension].

The aim of the study was to analyze the main parameters of vascular-thrombocyte hemostasis in patients with systolo-diastolic and isolated systolic arterial hypertension (SDAH and ISAH) aged over 65 years. The subjects were 201 elderly patients with AH. The study revealed that uncomplicated AH in the elderly was characterized by activation of vascular hemostasis and increase of thrombocyte aggregation ability, manifested by the increase of Willebrand factor level, the presence of spontaneous and irreversible aggregation, coincidence of the first and the second waves of aggregation, and intensification of aggregation in response to "moderate" and "strong" inductors.