Unearthing phytochemicals as natural inhibitors for pantothenate synthetase in : A computational approach.

Pantothenate synthetase protein plays a pivotal role in the biosynthesis of coenzyme A (CoA), which is a crucial molecule involved in a number of cellular processes including the metabolism of fatty acid, energy production, and the synthesis of various biomolecules, which is necessary for the survival of (). Therefore, inhibiting this protein could disrupt CoA synthesis, leading to the impairment of vital metabolic processes within the bacterium, ultimately inhibiting its growth and survival. This study employed molecular docking, structure-based virtual screening, and molecular dynamics (MD) simulation to identify promising phytochemical compounds targeting pantothenate synthetase for tuberculosis (TB) treatment.

Cytotoxic, antioxidant, antibacterial activity of phytochemicals from .

The cytotoxic, antioxidant, anticancer, and antibacterial properties of ethanolic extracts from is of interest. Plants of were gathered from the southern Saudi Arabian region of Albaha. extract was assessed using DPPH (2, 2-diphenyl-1-picrylhydrazyl).

Assessment of The Antibacterial Susceptibility of Ocimum basilicum.

       The current study was designed to assess the antibacterial activities of an ethanol extract of Ocimum basilicum (O. basilicum). Using disc diffusion and direct contact methods, the extracts were tested in vitro against three bacterial strains.

Nanostructured material-based optical and electrochemical detection of amoxicillin antibiotic.

The penicillin derivative amoxicillin (AMX) plays an important role in treating various types of infections caused by bacteria. However, excessive use of AMX may have negative health effects. Therefore, it is of utmost importance to detect and quantify the AMX in pharmaceutical drugs, biological fluids, and environmental samples with high sensitivity.

Deleterious effect of angiotensin-converting enzyme gene polymorphism in vitiligo patients.

Vitiligo is a rare skin condition caused by an immune reaction. Vitiligo can occur anywhere on the body. This proposed explanation of vitiligo makes it clear that vitiligo is not linked to any other autoimmune diseases.