The integration of microarray technologies and machine learning methods has become popular in predicting the pathological condition of diseases and discovering risk genes. Traditional microarray analysis considers pathways as a simple gene set, treating all genes in the pathway identically while ignoring the pathway network's structure information. This study proposed an entropy-based directed random walk (e-DRW) method to infer pathway activities.
View Article and Find Full Text PDFDeep neural networks (DNN) have remarkably progressed in applications involving large and complex datasets but have been criticized as a black-box. This downside has recently become a motivation for the research community to pursue the ideas of hybrid approaches, resulting in novel hybrid systems classified as deep neuro-fuzzy systems (DNFS). Studies regarding the implementation of DNFS have rapidly increased in the domains of computing, healthcare, transportation, and finance with high interpretability and reasonable accuracy.
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