Design, development, and characterization of amorphous rosuvastatin calcium tablets.

This work proposes a methodology for the design, development, optimisation, and evaluation of amorphous rosuvastatin calcium tablets (BCS class II drug). The main goal was to ensure rapid disintegration and high dissolution rate of the active ingredient, thus enhancing its bioavailability. The design started from a careful selection of excipients, which due to their characteristics and proportions within the formulation allowed the use of their properties such as fluidity or granulometric distribution.

Effect of hydrogeological and anthropogenic factors on the spatial and temporal distribution of CVOCs in the karst system of northern Puerto Rico.

This study evaluates factors affecting the spatial and temporal distribution of chlorinated volatile organic contaminants (CVOCs) in the highly productive aquifers of the karst region in northern Puerto Rico (KR-NPR). Historical records from 1982 to 2016 are analyzed using spatial and statistical methods to evaluate hydrogeological and anthropogenic factors affecting the presence and concentrations of multiple CVOCs in the KR-NPR. Results show extensive spatial and temporal distributions of CVOCs, as single entities and as mixtures.

The Teaching Interaction Procedure as a Staff Training Tool.

The teaching interaction procedure is an evidence-based procedure that has been utilized for the development of social skills. The teaching interaction procedure consists of labeling the targeted skill, providing a meaningful rationale for the importance of the skill, describing the steps of the targeted skill, modeling the skill, and providing feedback throughout the interaction. Although the teaching interaction procedure has been used to teach a variety of social skills to children and adolescents diagnosed with autism spectrum disorder (ASD) and other social and behavioral disorders, its use has not been evaluated for training staff.

The influence of hydrogeological and anthropogenic variables on phthalate contamination in eogenetic karst groundwater systems.

This study investigates the occurrence of six phthalates and distribution of the three most-detected phthalates in the karst region of northern Puerto Rico (KRNPR) using data from historical records and current field measurements. Statistical data analyses, including ANOVA, Chi-Square, and logistic regression models are used to examine the major factors affecting the presence and concentrations of phthalates in the KRNPR. The most detected phthalates include DEHP, DBP, and DEP.

An Evaluation of a Behaviorally Based Social Skills Group for Individuals Diagnosed with Autism Spectrum Disorder.

In this study we evaluated a social skills group which employed a progressive applied behavior analysis model for individuals diagnosed with autism spectrum disorder. A randomized control trial was utilized; eight participants were randomly assigned to a treatment group and seven participants were randomly assigned to a waitlist control group. The social skills group consisted of 32, 2 h sessions.