Publications by authors named "Norma Mongua-Rodriguez"

Objetivo: Estimar la prevalencia del antecedente de vacunación en adultos de 20 a 59 años y mayores de 60 años mediante autorreporte. Material y métodos. Análisis de datos obtenidos de la Encuesta Nacional de Salud y Nutrición 2022 (Ensanut 2022).

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  • El objetivo del estudio fue estimar el porcentaje de enfermedad diarreica aguda (EDA) en niños menores de cinco años en México, utilizando datos de la Encuesta Nacional de Salud y Nutrición Continua 2022.
  • La EDA afectó al 9.4% de los niños en el país, lo cual es similar a las cifras de 2000, y se observó que durante estos episodios, un 38.7% de los cuidadores disminuyeron la cantidad de alimentos ofrecidos.
  • Las conclusiones resaltan la necesidad urgente de mejorar estrategias de prevención y promoción de la salud para reducir la incidencia de EDA en esta población.
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Objetivo: Estimar el porcentaje de infección respiratoria aguda (IRA) en menores de cinco años en las últimas dos semanas en México, de acuerdo con los datos de la Encuesta Nacional de Salud y Nutrición Continua 2022 (Ensanut Continua 2022). Material y métodos. Se analizaron datos de la Ensanut Continua 2022.

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Objetivo: Describir las coberturas de vacunación en 2022 en niñas, niños y en adolescentes, así como comparar las prevalencias observadas con los datos de la Encuesta Nacional de Salud y Nutrición 2021 (Ensanut 2021). Material y métodos. Análisis de datos obtenidos de la Ensanut 2022.

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  • El estudio analiza el bienestar de hogares mexicanos con niños menores de cinco años que sufrieron enfermedad diarreica aguda (EDA) en las últimas dos semanas, usando datos de la Encuesta Nacional de Salud y Nutrición Continua 2022.
  • Se encontró que el 9.4% de estos niños presentó EDA, siendo más prevalente en hogares con bajo-medio bienestar y especialmente en niños de un año de edad.
  • Se concluye que es vital implementar medidas sanitarias que garanticen el acceso a agua potable tratada para prevenir la EDA y desarrollar políticas públicas integrales para proteger la salud infantil.
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Latin America continues to be severely underrepresented in genomics research, and fine-scale genetic histories and complex trait architectures remain hidden owing to insufficient data. To fill this gap, the Mexican Biobank project genotyped 6,057 individuals from 898 rural and urban localities across all 32 states in Mexico at a resolution of 1.8 million genome-wide markers with linked complex trait and disease information creating a valuable nationwide genotype-phenotype database.

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  • Tuberculosis (TB) is increasing among people with diabetes mellitus (DM), especially in lower-resource countries.
  • A trial in Mexico City tested TB preventive treatments using isoniazid (INH) and rifampicin (RIF) in individuals with type 2 DM, involving 130 participants.
  • The study was halted due to safety concerns; while the overall adverse event rates were similar, more participants on INH faced serious liver issues, while those on RIF had severe gastrointestinal problems, suggesting that neither treatment is safe enough for routine use in this population.
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Background: Vaccination against COVID-19 is a primary tool for controlling the pandemic. However, the spread of vaccine hesitancy constitutes a significant threat to reverse progress in preventing the disease. Studies conducted in Mexico have revealed that vaccination intention in Mexico among the general population ranges from 62 to 82%.

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  • The COVID-19 pandemic in Mexico started in February 2020, with mobility reduction as a key strategy for controlling the virus's spread.
  • Data on COVID-19 cases and mobility were analyzed from four selected states, using statistical models to assess how changes in mobility affected infection and death rates.
  • Results showed that increased mobility significantly raised the risk of COVID-19 cases and fatalities, with a 1% rise in mobility correlating to a 5.2% increase in incidence and a 2.9% increase in mortality, especially notable in cities like Mexico City and Jalisco.
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Current Genome-Wide Association Studies (GWAS) rely on genotype imputation to increase statistical power, improve fine-mapping of association signals, and facilitate meta-analyses. Due to the complex demographic history of Latin America and the lack of balanced representation of Native American genomes in current imputation panels, the discovery of locally relevant disease variants is likely to be missed, limiting the scope and impact of biomedical research in these populations. Therefore, the necessity of better diversity representation in genomic databases is a scientific imperative.

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Introduction: There is lack of information about predictive variables for pneumonia mortality in the Mexican population.

Objective: To identify a model for predictive variables for mortality in adults hospitalized with community acquired pneumonia (CAP).

Material And Methods: Case-control study of patients hospitalized with CAP.

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Measles continues to be one of the leading causes of child mortality worldwide, even though a highly effective vaccine has existed for more than 40 years. We aimed to describe the seroprevalence of measles antibodies in Mexico in 2012 and the risk factors associated with susceptibility. A total of 7,785 serum samples were analyzed from the National Health and Nutrition Survey in Mexico.

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Objective: To evaluate and compare vaccination coverage among children aged 12-23 and 24-35 months living in localities with less than 100 000 inhabitants in Encuesta Nacional de Salud y Nutrición (Ensanut) 2012 and Ensanut 100k (2018).

Materials And Methods: Estimate of coverage with both surveys.

Results: Between 2012 and 2018, according to proof and self-report, the coverage of the basic scheme was maintained in children aged 12-23 (51.

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  • - Comparisons were made between the prevalence of acute respiratory infections (ARI) and acute diarrheal disease (ADD) among children under five in localities with populations under 100,000 in two surveys: Ensanut 2012 and Ensanut 100k (2018).
  • - The prevalence of ARI dropped from 45.1% in 2012 to 32.9% in 2018, especially among medium and high-income households; however, there were no significant changes for ADD prevalence.
  • - Factors linked to ARI in lower-income households included roofing materials and weather conditions, while ADD was associated with a lack of piped water, highlighting environmental influences on these health issues.
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Background: An essential component of the "Polio Eradication and Endgame Strategic Plan 2013-2018" is the evaluation of population immunity. Mexico introduced the inactivated polio vaccine (IPV) into its routine immunization schedule in 2007 but continued to give trivalent oral polio vaccine OPV twice a year during National Health Weeks through 2016.

Methods: To describe the seroprevalence of poliomyelitis among children one to four years old in Mexico and analyze risk factors for susceptibility.

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Background: Genotyping and georeferencing in tuberculosis (TB) have been used to characterize the distribution of the disease and occurrence of transmission within specific groups and communities.

Objective: The objective of this study was to test the hypothesis that diabetes mellitus (DM) and pulmonary TB may occur in spatial and molecular aggregations.

Material And Methods: Retrospective cohort study of patients with pulmonary TB.

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Background: Mexico introduced inactivated polio vaccine (IPV) into its routine immunization (RI) schedule in 2007 but continued to give trivalent oral polio vaccine (tOPV) twice a year during national health weeks (NHW) through 2015.

Objectives: To evaluate individual variables associated with poliovirus (PV) shedding among children with IPV-induced immunity after vaccination with tOPV and their household contacts.

Materials And Methods: We recruited 72 children (both genders, ≤30 months, vaccinated with at least two doses of IPV) and 144 household contacts (both genders, 2 per household, children and adults) between 08/2010 and 09/2010 in Orizaba, Veracruz.

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  • The study investigates the link between diabetes mellitus (DM) and tuberculosis (TB), noting that DM patients may have a higher likelihood of poor TB outcomes.
  • A systematic review and meta-analysis were conducted to assess if patients with both DM and pulmonary TB cluster genetically more than those with TB alone.
  • Specific keyword searches resulted in the inclusion of studies that met certain criteria, focusing on molecular clustering in patient populations with confirmed pulmonary TB.
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Background: Respiratory manifestations of HIV disease differ globally due to differences in current availability of effective highly active antiretroviral therapy (HAART) programs and epidemiology of infectious diseases.

Objective: To describe the association between HAART and discharge diagnosis and all-cause in-hospital mortality among hospitalized patients with infectious respiratory disease and HIV/AIDS.

Material And Methods: We retrospectively reviewed the records of patients hospitalized at a specialty hospital for respiratory diseases in Mexico City between January 1st, 2010 and December 31st, 2011.

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Background: Tuberculosis (TB) remains a public health problem in Mexico while the incidence of diabetes mellitus type 2 (DM) has increased rapidly in recent years.

Objective: To describe the trends of incidence rates of pulmonary TB associated with DM and not associated with DM and to compare the results of treatment outcomes in patients with and without DM.

Materials And Methods: We analysed the National Tuberculosis Registry from 2000 to 2012 including patients with pulmonary TB among individuals older than 20 years of age.

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Treatment of persons with latent tuberculosis (TB) infection at greatest risk of reactivation is an important component of TB control and elimination strategies. Biomarkers evaluating the effectiveness of treatment of latent TB infection have not yet been identified. This information would enhance control efforts and assist the evaluation of new treatment regimes.

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Background: Recently, the World Health Organisation and the International Union Against Tuberculosis and Lung Disease published a Collaborative Framework for the Care and Control of Tuberculosis (TB) and Diabetes (DM) (CFTB/DM) proposing bidirectional screening and joint management.

Objective: To evaluate the feasibility and effectiveness of the CFTB/DM in Mexico.

Design: Prospective observational cohort.

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Background: Despite chemotherapy, patients with cured pulmonary tuberculosis may result in lung functional impairment.

Objective: To evaluate a novel scoring system based on the degree of radiographic abnormalities and related spirometric values in patients with cured pulmonary tuberculosis.

Methods: One hundred and twenty seven patients with cured pulmonary tuberculosis were prospectively enrolled in a referral hospital specializing in respiratory diseases.

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Objective: To evaluate the impact of rubella vaccination strategies on the rates of acquired rubella and congenital rubella syndrome in the Americas.

Methods: We conducted a systematic review of the literature (MEDLINE, PubMed, EMBASE, Cochrane Library, Artemisa Database, LILACS Database, Evidence Portal, VHL-PAHO Portal, Scielo, and Grey-Literature sources) that was published from 1969-2010. We included studies on rubella incidence and seroprevalence rates that were associated with rubella vaccination.

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