Inhibition of the Growth of and Microorganisms in Aesthetic Orthodontic Brackets through the In Situ Synthesis of Ag, TiO and Ag/TiO Nanoparticles.

Plaque control is especially important during orthodontic treatment because areas of the teeth near brackets and wires are difficult to clean with a toothbrush, resulting in debris buildup of food or dental plaque, thus causing caries and periodontal disease. The objective of this study was to evaluate the antimicrobial properties of silver nanoparticles (AgNPs), titanium dioxide nanoparticles (TiONPs), and silver/titanium dioxide nanoparticles (Ag/TiONPs), synthesized on the surface of α-alumina ceramic brackets. The AgNPs and TiONPs were synthesized by a simple chemical method, and these were characterized by XRD, SEM, and XPS TEM; the antimicrobial activity was tested against and by diffusion test.

Effect of three fluoride compounds on the growth of oral normal and tumor cells.

Aim: Comparative study of the growth inhibition by different types of fluoride compounds used in dentistry has been limited. We investigated the effects of sodium fluoride (NaF), diammine silver fluoride [Ag(NH3)2F] and 5-fluorouracil (5-FU) on the growth of eleven human normal and tumor cells in total.

Materials And Methods: Viable cell number was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay.