Publications by authors named "Norma Angelica Oviedo de Anda"
Article Synopsis
- A study focused on the prevalence of genetic rearrangements associated with a good prognosis in children with acute lymphoblastic leukemia (ALL) in Mexico found lower rates compared to Caucasian populations.
- Researchers developed a new TaqMan RT-qPCR method to assess four specific genetic rearrangements in Hispanic children with ALL from Mexico City.
- The findings revealed a low prevalence of these rearrangements (7.7%, 3.3%, and 2.8%), aligning with previous studies on Mexican and Hispanic children, highlighting the need to further understand genetic factors in ALL among diverse populations.
Lambda bacteriophage development is impaired in Escherichia coli cells defective for peptidyl (pep)-tRNA hydrolase (Pth). Single-base-pair mutations (bar(-)) that affect translatable two-codon open reading frames named bar minigenes (barI or barII) in the lambda phage genome promote the development of this phage in Pth-defective cells (rap cells). When the barI minigene is cloned and overexpressed from a plasmid, it inhibits protein synthesis and cell growth in rap cells by sequestering tRNA(2)(Ile) as pep-tRNA(2)(Ile).
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