Effects of MAO-A and CYP450 on primaquine metabolism in healthy volunteers.

Eliminating the Plasmodium vivax malaria parasite infection remains challenging. One of the main problems is its capacity to form hypnozoites that potentially lead to recurrent infections. At present, primaquine is the only drug used for the management of hypnozoites.

Factors Affecting Primaquine Combination Treatment in Malaria Patients in Selangor, Malaysia.

Introduction: Primaquine is vital for the management of liver-stage and malaria. However, primaquine effectiveness is dependent on various factors and differs between populations. Therefore, this study was conducted to identify factors that affect the length of stay and relapse during primaquine combination treatment in malaria-infected patients in the local setting.

Prevalence of nosocomial infection and antibiotic use at a university medical center in Malaysia.

Background And Objective: Most reports of nosocomial infection (NI) prevalence have come from developed countries with established infection control programs. In developing countries, infection control is often not as well established due to lack of staff and resources. We examined the rate of NI in our institution.