Spontaneously generated large adipose flaps in vivo tissue engineering chambers.

Aim: Previous experiments using our in vivo tissue engineering chamber (TEC) model demonstrated that adipose flap was spontaneously generated without the need for adipocyte or stem cell implantation. The purposes of the present study are to clarify 1) the reproducibility of this method to create adipose flaps, 2) the time-course of adipogenesis, and 3) the long-term stability of the adipose flap generated.

Methods: The chambers that afforded a protected space for tissue growth were implanted into the groins of rabbits.

Effects of flow patterns and hemodynamic force on vascular endothelium in the temporary arteriovenous shunt loop in rabbits.

The purpose of this study was to investigate whether there is a risk of thrombosis in the temporary arteriovenous shunt loop (TAVSL). The authors established a TAVSL model in the rabbit. Experimental groups were divided into non-heparin treated and heparin treated.