Publications by authors named "Norimasa Nakamoto"
Bioconjug Chem
August 2015
Article Synopsis
- Researchers are exploring cell-penetrating peptide-linked polymers to enhance the delivery of biomolecules into cells, focusing on a specific polymer that previously showed promise in in vivo studies.
- The study tested this polymer using plasmid DNA encoding green fluorescent protein, β-galactosidase, and bovine serum albumin to evaluate its effectiveness in enhancing cellular uptake.
- Results indicated that the ratio of polymers to pGFP-C1 was crucial for internalization, with higher ratios leading to increased expression of GFP, while β-galactosidase and BSA exhibited different internalization behaviors based on their interactions with the polymers.
