Photoinduced adsorption of oligonucleotides on polyvinyl chloride films containing malachite green derivative.

DNA adsorption on the micrometer scale in a simple and cost-effective manner has received considerable interest. We prepared a film by casting an organic solvent containing polyvinyl chloride and a malachite green derivative, which can be photoionized to afford a cationic moiety for interaction with DNA. In this article, we report photoinduced oligonucleotide adsorption on a film that offers spatial and temporal control over oligonucleotide adsorption.

Photoinduced binding of malachite green copolymer to parallel G-quadruplex DNA.

Designing ligands that selectively target G-quadruplex DNAs has gained attention due to their possible roles in regulation of gene expression and as anti-cancer agents. In this article, we report irradiation-induced ligand binding to G-quadruplex DNAs which offers a novel approach to targeting specific G-quadruplexes. Photoinduced binding to G-quadruplex DNAs was observed for copolymers of poly(vinyl alcohol) carrying a malachite green moiety (PVAMG).

Irradiation-induced fusion between giant vesicles and photoresponsive large unilamellar vesicles containing malachite green derivative.

Light-initiated fusion between vesicles has attracted much attention in the research community. In particular, fusion between photoresponsive and non-photoresponsive vesicles has been of much interest in the development of systems for the delivery of therapeutic agents to cells. We have performed fusion between giant vesicles (GVs) and photoresponsive smaller vesicles containing malachite green (MG) derivative, which undergoes ionization to afford a positive charge on the molecule by irradiation.