Publications by authors named "Norikazu Kainuma"
Background/aims: We investigated what can be revealed by extending the sensitivity of HBsAg detection to below the present limit.
Methods: We examined the sensitivity of this immunoassay in comparison with real-time PCR detection of HBV DNA using serially diluted sera from HBV carriers. Low HBsAg was measured in 210 healthy volunteers and 368 patients with non-B chronic liver diseases who were negative for HBsAg by a standard EIA method.