Publications by authors named "Norihiro Yuasa"

Background: Few studies have examined the prognosis of long-term gastric cancer (GC) survivors after gastrectomy. This study aimed to identify the prognostic factors for 5-year recurrence-free survivors after gastrectomy for GC.

Methods: A total of 721 patients with pathological stage Ⅰ-Ⅲ GC who underwent gastrectomy between 2005 and 2018 and survived for 5 years without recurrence were enrolled.

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A 54-year-old woman was referred to our hospital because of abnormal colonoscopic findings, including a submucosal protuberance at the appendiceal root. A biopsy showed no malignant findings. Computed tomography revealed a 20-mm cystic lesion with thick walls at the appendiceal root, suggestive of an appendiceal mucocele.

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We encountered a rare case of appendiceal carcinoma associated with Amyand's hernia, which was difficult to diagnose preoperatively. A 74-year-old man presented to our hospital with right lower abdominal pain. A hard mass was palpable in the right lower abdomen, and blood tests showed a slightly elevated inflammatory response.

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Context: Few studies have compared the prognostic value of scoring systems based on physical and blood parameters in terminally ill patients with cancer.

Objectives: This study evaluated the prognostic abilities of Palliative Prognostic Index (PPI), Laboratory Prognostic Score (LPS), and Palliative Prognostic Score (PaP).

Methods: We included 989 terminally ill patients with cancer who consulted for admission to our palliative care unit.

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Purpose: One-year mortality is important for referrals to specialist palliative care or advance care planning (ACP). This helps optimize comfort for those who cannot be cured or have a lower life expectancy. Few studies have investigated the risk factors for 1-year mortality after gastrectomy for gastric cancer (GC).

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Purpose: Despite their similar clinical characteristics, appendiceal diverticulitis (AD) and acute appendicitis (AA) are pathologically distinct. This study compared the clinical features of AD and AA and identified relevant risk factors.

Methods: Patients who underwent appendectomy with a preoperative diagnosis of either AD or AA were categorized based on histopathological findings.

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Background: Preoperative pulmonary function assessment is useful for selecting surgical candidates and operative methods and assessing the risk of postoperative pulmonary complications. However, few studies have investigated the relationship between preoperative pulmonary function and short- and long-term outcomes in patients who underwent gastrectomy for gastric cancer.

Methods: Of the 1040 patients with gastric cancer (stages I-III) who had undergone R0 gastrectomy between 2009 and 2020, 750 who underwent preoperative spirometry were included.

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A 74-year-old woman underwent right hemicolectomy and partial ileal resection for ascending colon cancer with synchronous peritoneal metastasis. Histopathological examination showed moderately differentiated adenocarcinoma with mucinous component, pT4b N3 M1, and Stage IV. Postoperative chemotherapy comprising 36 courses of mFOLFOX6 with bevacizumab was administered.

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Background: Collision tumors are a subtype of simultaneous tumors wherein two unrelated tumors collide or infiltrate each other. Collision gastric adenocarcinomas (CGA) are rare and difficult to diagnose, and their clinical implications remain unclear. Herein, we aimed to reveal diagnostic methods for CGA and provide insight into its implications.

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A 78-year-old man presented to our hospital with loss of appetite and epigastric discomfort. Computed tomography (CT) revealed dilation of the main pancreatic duct and three cystic lesions in the pancreatic neck, body, and tail. Endoscopic ultrasonography showed a mural nodule > 5 mm enhanced with Sonazoid in a cyst.

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Aim: There is a concern that the differential diagnosis of a groin mass depends on a physicians' subjective judgment and experience. We aimed to clarify the significance of US in the diagnosis of a groin mass.

Material And Methods: This retrospective study included 1,898 patients who underwent US examination of a groin mass.

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This study determined prognostic factors by comparing clinico-bacterial factors based on significant elevated serum procalcitonin levels in patients with suspected bloodstream infection (BSI). We retrospectively analyzed the medical records of 1,052 patients (age ≥16 years) with fever (temperature ≥38°C) and serum procalcitonin levels of ≥2.0 ng/mL, and blood culture results.

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We encountered a rare case of a pancreatic head tumor protruding into the portal vein, later diagnosed histopathologically as primary leiomyosarcoma of the portal vein. A 59-year-old woman visited our hospital because of an elevated amylase level during a medical checkup. Computed tomography showed a moderately contrasted, well-defined mass of 35-mm diameter in the pancreatic head with protrusion into the portal vein.

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An 83-year-old man visited our hospital because of difficulty swallowing. Gastroscopy revealed multiple ulcers and a reddish depression in the lesser curvature of the middle stomach. The initial biopsy showed regenerative atypia, so a gastroscopy was repeated every 3 months thereafter because of suspected malignancy.

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A new classification of SMARCA4-deficient tumors was proposed recently for thoracic malignancies, and the tumors have some histopathological characteristics similar to those of carcinosarcoma. We encountered a case of SMARCA4-deficient rectal carcinoma with a sarcomatoid component. A 46-year-old man presented to our hospital with a prolapsing anal mass.

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Article Synopsis
  • A study aimed to create a scoring system to predict short-term survival in terminally ill patients with gastrointestinal (GI) malignancy using 19 blood parameters.
  • Researchers analyzed data from 816 patients and identified 5 significant blood indices that are linked to 14-day survival rates.
  • The developed GI laboratory prognostic score (GI-LPS) demonstrated reliable accuracy and can enhance traditional prognostic assessments for these patients.
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Article Synopsis
  • A study analyzed 649 terminally ill patients with respiratory cancer to create a scoring system aimed at predicting 14-day survival rates based on blood test results.
  • Significant prognostic factors were identified, including specific levels of C-reactive protein, aspartate aminotransferase, blood urea nitrogen, and others, leading to the establishment of a laboratory prognostic score (R-LPS).
  • The R-LPS demonstrated a reasonable accuracy for predicting short-term mortality, with a sensitivity range of 75-82% and specificity of 59-62%, suggesting its effectiveness for use in a palliative care setting.
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Background: Emergency appendectomy is often performed for de Garengeot hernia. However, in some cases, there may be a chance to perform an appendix-preserving elective surgery.

Case Description: A 76-year-old woman presented to our hospital with complaints of a right inguinal swelling, which we diagnosed as a de Garengeot hernia using computed tomography (CT).

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An intestinal knot is a rare cause of intestinal obstruction. We report a rare case of strangulating bowel obstruction due to a small intestinal knot. A 69-year-old man who had an end colostomy was admitted with severe abdominal pain and vomiting.

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Purpose: This unicentric, retrospective cohort study aimed to identify the optimal cutoff values of preoperative serum carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) for the prognosis in patients with stage II/III colon cancer.

Methods: After excluding 43 patients with CA19-9 levels < 0.2 U/mL, 588 were included.

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Article Synopsis
  • A study was conducted on 73 terminally ill patients with gynecologic malignancy to create a scoring system to predict short-term survival.
  • Six significant laboratory indices were identified as independent factors for 14-day mortality, including levels of C-reactive protein and sodium.
  • The newly developed scoring system (G-LPS) showed a sensitivity of 72% and specificity of 79%, indicating it can effectively predict 14-day survival for these patients.
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We encountered a rare case that involved the superficial spreading type of early gastric cancer coexisting with multiple hyperplastic polyps. An 81-year-old Japanese woman with a history of Helicobacter pylori infection was diagnosed with gastric cancer (cT1bN0M0), which presented as a wide, nodular, aggregated protrusion that was associated with multiple pedunculated and sessile polyps. Distal gastrectomy was performed, and the resected specimen involved an 8 cm × 4 cm nodular aggregated protruding lesion and 15 polyps that were 2-20 mm in size.

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Article Synopsis
  • De Garengeot hernia is a rare condition where the appendix is trapped in a femoral hernia, and this study examines its clinical and pathological features.
  • The research involved six patients over nearly two decades, with a 3.2% incidence rate among femoral hernias, predominantly affecting elderly women with various forms of appendicitis.
  • Diagnosis prior to surgery is challenging, and many patients present with serious appendicitis, indicating that urgent intervention is often necessary based on the condition's severity.
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We describe a case of a mucosal prolapse syndrome (MPS)-like inflammatory polyp protruding from the appendiceal orifice, mimicking an appendiceal neoplasm. A 48-year-old man presented with lower abdominal pain and elevated white blood cell count and C-reactive protein level. Computed tomography showed a swollen appendix with multiple small saccular lesions and periappendiceal fat stranding and small saccular lesions in the ascending colon and cecum.

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Background: Due to prognostic heterogeneity within a stage of gastric cancer (GC), identification of patients with a high risk for recurrence after resection is important. We aimed to identify the prognostic significance of preoperative serum carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) levels in patients with Stage I, II, and III GC who underwent R0 gastrectomy.

Methods: A total of 794 patients were included in this study after excluding 72 patients with CA19-9 <1.

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