Publications by authors named "Norboo Angchuk"

Article Synopsis
  • A study was conducted on 2,800 Ladakhi individuals in Northern India to investigate the prevalence of hypertension and how factors like altitude, lifestyle changes, and urbanization affect it.
  • Results showed that hypertension affected 37.0% of participants, with the highest rates found in urban migrants (48.3%), while rural nomads at high altitudes had lower rates (27.7%).
  • Key factors associated with higher hypertension rates included aging, obesity, urban living, and modern occupations, indicating that both lifestyle changes and high-altitude living independently contribute to hypertension.
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Aim: We did a population-based cross-sectional study to investigate the prevalence and risk factors of gastroesophageal reflux disease (GERD) in a high altitude area.

Methods: An observational study using a validated questionnaire consisting of demographic, lifestyle and dietary characteristics was administered in an interview based format by two clinicians on a sample of adult population residing in urban area and rural high altitude areas of Ladakh. Presence of GERD was defined as a score of ≥4 using a previously validated symptom score based on the severity and frequency of heartburn and regurgitation.

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The study of the biology of evolution has been confined to laboratories and model organisms. However, controlled laboratory conditions are unlikely to model variations in environments that influence selection in wild populations. Thus, the study of "fitness" for survival and the genetics that influence this are best carried out in the field and in matching environments.

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