Publications by authors named "Norberto Sanchez-Escobar"
Analytical study of , , , , and in Mexican children with acute myeloid leukemia: A multicenter study of the Mexican interinstitutional group for the identification of the causes of childhood leukemia (MIGICCL).
Omar Sepúlveda-Robles Elva Jiménez-Hernández Victoria Domínguez-Catzín Eber Gómez-Flores Jorge Alfonso Martín-Trejo
Front Pediatr
November 2022
Background: The distribution of , , , , and in the pediatric population with acute myeloid leukemia (AML) in many countries of Latin America is largely unknown. Therefore, we aimed to investigate the frequency of these fusion genes in children with AML from Mexico City, which has one of the highest incidence rates of acute leukemia in the world. Additionally, we explored their impact in mortality during the first year of treatment.
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- A study focused on the prevalence of genetic rearrangements associated with a good prognosis in children with acute lymphoblastic leukemia (ALL) in Mexico found lower rates compared to Caucasian populations.
- Researchers developed a new TaqMan RT-qPCR method to assess four specific genetic rearrangements in Hispanic children with ALL from Mexico City.
- The findings revealed a low prevalence of these rearrangements (7.7%, 3.3%, and 2.8%), aligning with previous studies on Mexican and Hispanic children, highlighting the need to further understand genetic factors in ALL among diverse populations.