Lyme carditis--diagnosis, treatment and prognosis.

Background: There are 60,000 to 100,000 new cases of borreliosis in Germany each year. This infectious disease most commonly affects the skin, joints, and nervous system. Lyme carditis is a rare manifestation with potentially lethal complications.

No evidence for involvement of prothrombotic platelet receptor polymorphisms in acute coronary stent thrombosis.

Polymorphisms of receptors involved in platelet adhesion and aggregation modulate platelet thrombogenicity and were found to predispose to premature arterial thromboses in individuals at risk. In our current study, we assessed the potential relevance of prothrombotic platelet receptor polymorphisms for the pathogenesis of acute coronary stent thrombosis. Comparing the genotype prevalences of respective polymorphisms in patients with acute coronary stent thrombosis and healthy control subjects, our data do not indicate an increased risk of carriers of prothrombotic variants of platelet receptors for this complication.

[Foundation of a Health Care Ethics Committee (HEC) in a nonconfessional hospital. Initial experiences and prospects of the future].

Background: Whereas Health Care Ethics Committees (HECs) are well established in the USA, they are still an exception in Germany. In this study, the authors report of the implementation of an HEC at the SLK Hospital Heilbronn, Germany, and discuss the further development within the first 2 years.

Implementation And Projects: After a 1-year preparatory period the official establishment of the HEC followed in March 2004.

[Spontaneous coronary spasm as a rare cause of survived sudden cardiac death].

Case Report: A 39-year-old man was admitted to our intensive care unit after successful resuscitation because of ventricular fibrillation with clinical and electrographic signs of acute myocardial infarction. Coronary angiography showed normal coronary arteries. MINC syndrome (myocardial infarction with angiographically normal coronary arteries) was due to a severe proximal spontaneous spasm of the left anterior descending artery (LAD).